Reactome | ANTXR1-1 [endosome membrane]

ANTXR1-1 [endosome membrane]

Stable Identifier

R-HSA-5210914

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Synonyms

Anthrax toxin receptor 1 isoform 1, TEM8 isoform 1, Tumor endothelial marker 8 isoform 1

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Literature References

PubMed ID	Title	Journal	Year
12468536	Cell surface tumor endothelium marker 8 cytoplasmic tail-independent anthrax toxin binding, proteolytic processing, oligomer formation, and internalization Leppla, SH, Liu, S	J. Biol. Chem.	2003

External Reference Information

External Reference

UniProt:Q9H6X2-1 ANTXR1

Gene Names

ANTXR1, ATR, TEM8

Other Identifiers

11718523_s_at

11726830_at

11726831_at

11738857_at

16881031

16881059

220092_PM_s_at

220092_s_at

220093_PM_at

220093_at

224694_PM_at

224694_at

227660_PM_at

227660_at

2487083

2487084

2487085

2487089

2487091

2487096

2487097

2487099

2487100

2487104

2487113

2487116

2487117

2487118

2487119

2487130

2487131

2487141

2487142

2487143

2487144

2487145

2487146

2487152

2487153

2487162

2487165

2487173

2487174

2487177

2487210

2487211

2487212

2487213

2487214

2487215

2487216

2487217

2487218

2487219

51033_at

57718_at

77387_at

8042439

84168

A_14_P106122

A_14_P108434

A_23_P84576

A_24_P131522

A_24_P208595

GE56034

GO:0001568

GO:0004888

GO:0005515

GO:0005518

GO:0005768

GO:0005886

GO:0007010

GO:0007155

GO:0008092

GO:0009897

GO:0009986

GO:0010008

GO:0016020

GO:0022414

GO:0030036

GO:0030198

GO:0031258

GO:0031410

GO:0031527

GO:0034446

GO:0038023

GO:0042995

GO:0043226

GO:0046872

GO:0048856

GO:0051015

GO:0060089

GO:1901202

HMNXSV003000912

HMNXSV003004817

HMNXSV003006435

Hs.42927.0.S1_3p_at

Hs.8966.0.A1_3p_at

ILMN_1670379

ILMN_1780894

ILMN_1811877

ILMN_2387995

PH_hs_0023373

TC02000403.hg

TC02000404.hg

g8922545_3p_at

Participates

as a member of

ANTXR1 [endosome membrane] (Homo sapiens)

Other forms of this molecule

ANTXR1-1 [plasma membrane]

Cross References

RefSeq

NP_115584.1, NP_060623.2, NP_444262.1

OpenTargets

ENSG00000169604

GeneCards

Q9H6X2

HPA

ENSG00000169604-ANTXR1

Ensembl

ENSP00000301945, ENST00000303714, ENSP00000387058, ENSG00000169604, ENSP00000506719, ENST00000409829, ENST00000409349, ENST00000463335, ENSP00000386494

PRO

Q9H6X2

Pharos - Targets

Q9H6X2

Orphanet

22118

HMDB Protein

HMDBP02645

PDB

6ADM, 3N2N, 6ADR, 6ADL, 6CX1

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q16625 OCLN	4	OCLN [cell junction] (R-HSA-2160944) OCLN(1-320) [plasma membrane] (R-HSA-351854) OCLN(321-522) [plasma membrane] (R-HSA-351873) OCLN [plasma membrane] (R-HSA-351846)	0.527	2
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.527	2
UniProt:Q14554 PDIA5	1	PDIA5 [endoplasmic reticulum membrane] (R-HSA-535514)	0.527	3
UniProt:Q14627 IL13RA2	1	IL13RA2 [extracellular region] (R-HSA-449666)	0.527	2
UniProt:P11021 HSPA5	6	HSPA5 [extracellular region] (R-HSA-351322) HSPA5 [endoplasmic reticulum lumen] (R-HSA-387190) HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [cytosol] (R-HSA-5252115) HSPA5 [nucleoplasm] (R-HSA-5252042) HSPA5 [lumenal side of endoplasmic reticulum membrane] (R-HSA-985498)	0.527	3
UniProt:P50548 ERF	3	p-T526-ERF [nucleoplasm] (R-HSA-3209166) p-T526-ERF [cytosol] (R-HSA-3209167) ERF [nucleoplasm] (R-HSA-2534321)	0.527	2