Reactome | ANTXR2-4 [plasma membrane]

ANTXR2-4 [plasma membrane]

Stable Identifier

R-HSA-5210023

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Anthrax toxin receptor 2 isoform 4, CMG2 isoform 4, Capillary morphogenesis gene 2 protein isoform 4

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
12700348	Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor Young, JA, Scobie, HM, Rainey, GJ, Bradley, KA	Proc. Natl. Acad. Sci. U.S.A.	2003

External Reference Information

External Reference

UniProt:P58335-4 ANTXR2

Gene Names

ANTXR2, CMG2

Participates

as a candidate of

ANTXR2 [plasma membrane] (Homo sapiens)

Other forms of this molecule

ANTXR2-4 [endosome membrane]

Cross References

ENSEMBL

ENST00000403729, ENSP00000385575, ENSP00000306185, ENSG00000163297, ENST00000681115, ENST00000307333, ENSP00000505618, ENST00000346652, ENSP00000314883

OpenTargets

ENSG00000163297

GeneCards

ANTXR2

HPA

ENSG00000163297-ANTXR2

PRO

P58335

Pharos - Targets

P58335

GlyGen

P58335

Orphanet

ANTXR2

HMDB Protein

HMDBP07449

PDB

1SHU, 1SHT, 1TZN, 8FZ4, 1T6B, 8FT6, 8FT8, 7N1O, 8FZU, 8FZV

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13423 pagA	5	pagA(197-794) [plasma membrane] (R-BAN-5205715) PA63 [endosome membrane] (R-BAN-5210910) pagA [plasma membrane] (R-BAN-5205702) pagA(30-196) [extracellular region] (R-BAN-5205700) pagA [extracellular region] (R-BAN-5205707)	0.786	7
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.519	2
UniProt:O75581 LRP6	8	LRP6 [plasma membrane] (R-HSA-206252) p-4S,3T,T1479,S1490,T1493-LRP6 [plasma membrane] (R-HSA-1458895) p-2S,S1490,2T-LRP6 [plasma membrane] (R-HSA-1458894) LRP6N [extracellular region] (R-HSA-5334021) p-LRP6 [early endosome membrane] (R-HSA-5368496) LRP6 [early endosome membrane] (R-HSA-5368481) p-S1490-LRP6 [plasma membrane] (R-HSA-206156) p-T1479,S1490,T1493-LRP6 [plasma membrane] (R-HSA-205884)	0.463	2

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