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pagA:ANTXR2 [plasma membrane]
Stable Identifier
R-HSA-5210007
Type
Complex
Species
Homo sapiens
Related Species
Bacillus anthracis
Compartment
plasma membrane
Synonyms
PA83:ANTXR2
GO Cellular Component
host cell plasma membrane
(0020002)
Locations in the PathwayBrowser
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Uptake and actions of bacterial toxins (Homo sapiens)
Uptake and function of anthrax toxins (Homo sapiens)
Furin cleaves ANTXR2-bound pagA to yield pagA(197-794) (Homo sapiens)
pagA:ANTXR2 [plasma membrane] (Homo sapiens)
pagA binds ANTXR2 (Homo sapiens)
pagA:ANTXR2 [plasma membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
15243628
Crystal structure of a complex between anthrax toxin and its host cell receptor
Santelli, E
,
Leppla, SH
,
Liddington, RC
,
Bankston, LA
Nature
2004
Participants
components
ANTXR2 [plasma membrane]
(Homo sapiens)
pagA:Ca2+ [plasma membrane]
(Bacillus anthracis)
Participates
as an output of
pagA binds ANTXR2 (Homo sapiens)
as an input of
Furin cleaves ANTXR2-bound pagA to yield pagA(197-794) (Homo sapiens)
Disease
Name
Identifier
Synonyms
anthrax disease
DOID:7427
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