Reactome | ANTXR2-1 [plasma membrane]

ANTXR2-1 [plasma membrane]

Stable Identifier

R-HSA-5205722

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Anthrax toxin receptor 2 isoform 1, CMG2 isoform 1, Capillary morphogenesis gene 2 protein isoform 1

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
12700348	Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor Young, JA, Scobie, HM, Rainey, GJ, Bradley, KA	Proc. Natl. Acad. Sci. U.S.A.	2003

External Reference Information

External Reference

UniProt:P58335-1 ANTXR2

Gene Names

ANTXR2, CMG2

Other Identifiers

11736046_at

11736047_a_at

11736048_at

11749856_a_at

118429

1555536_3p_at

1555536_PM_at

1555536_at

16977251

225524_PM_at

225524_at

228573_PM_at

228573_at

238050_PM_at

238050_at

2774992

2774993

2774994

2774995

2774996

2774997

2774998

2774999

2775000

2775001

2775008

2775009

2775013

2775014

2775015

2775016

2775017

2775018

2775019

2775023

2775024

2775025

2775026

2775030

2775031

2775032

2775035

2775036

2775037

2775038

2775039

2775040

2775041

2775042

2775043

2775044

2775045

2775046

2775047

2775071

51714_at

58617_at

8101260

88490_at

A_19_P00801014

A_19_P00807952

A_24_P345846

A_24_P377144

GE56429

GE829190

GO:0004888

GO:0005515

GO:0005576

GO:0005783

GO:0005789

GO:0005886

GO:0009986

GO:0010008

GO:0016020

GO:0038023

GO:0043226

GO:0046872

GO:0060089

HMNXSV003045512

HMNXSV003051192

Hs.270263.0.A1_3p_at

Hs.5897.0.S1_3p_a_at

Hs.5897.0.S1_3p_at

Hs.5897.1.S1_3p_at

Hs2.5897.3.S1_3p_at

Hs2.5897.3.S1_3p_s_at

ILMN_1812926

PH_hs_0030923

TC04001328.hg

Participates

as a member of

ANTXR2 [plasma membrane] (Homo sapiens)

Other forms of this molecule

ANTXR2-1 [endosome membrane]

Cross References

ENSEMBL

ENST00000403729, ENSP00000385575, ENSP00000306185, ENSG00000163297, ENST00000681115, ENST00000307333, ENSP00000505618, ENST00000346652, ENSP00000314883

OpenTargets

ENSG00000163297

GeneCards

ANTXR2

HPA

ENSG00000163297-ANTXR2

PRO

P58335

Pharos - Targets

P58335

GlyGen

P58335

Orphanet

ANTXR2

HMDB Protein

HMDBP07449

PDB

1SHU, 1SHT, 1TZN, 8FZ4, 8FT8, 1T6B, 8FT6, 7N1O, 8FZU, 8FZV

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13423 pagA	5	pagA(197-794) [plasma membrane] (R-BAN-5205715) PA63 [endosome membrane] (R-BAN-5210910) pagA [plasma membrane] (R-BAN-5205702) pagA(30-196) [extracellular region] (R-BAN-5205700) pagA [extracellular region] (R-BAN-5205707)	0.786	7
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.519	2
UniProt:O75581 LRP6	8	LRP6 [plasma membrane] (R-HSA-206252) p-4S,3T,T1479,S1490,T1493-LRP6 [plasma membrane] (R-HSA-1458895) p-2S,S1490,2T-LRP6 [plasma membrane] (R-HSA-1458894) LRP6N [extracellular region] (R-HSA-5334021) p-LRP6 [early endosome membrane] (R-HSA-5368496) LRP6 [early endosome membrane] (R-HSA-5368481) p-S1490-LRP6 [plasma membrane] (R-HSA-206156) p-T1479,S1490,T1493-LRP6 [plasma membrane] (R-HSA-205884)	0.463	2