p62 links damaged mitochondria to LC3

Stable Identifier
R-HSA-5205649
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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p62 links to the microtubule-associated protein Autophagy marker Light Chain 3 (LC3). This begins the recruitment of the autophagy machinery to the damaged mitochondria, targeting it for autophagic degradation.

Literature References
PubMed ID Title Journal Year
20712405 Autophagosome formation and molecular mechanism of autophagy

Tanida, I

Antioxid. Redox Signal. 2011
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created