Reactome | CFD [extracellular region]

CFD [extracellular region]

Stable Identifier

R-HSA-51919

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Complement factor D precursor , C3 convertase activator, Properdin factor D, Adipsin

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P00746 CFD

Gene Names

CFD, DF, PFD

Chain

signal peptide:1-20, propeptide:21-25, chain:26-253

Reference Genes

BioGPS Gene:1675 CFD

COSMIC (genes):CFD CFD

CTD Gene:1675 CFD

dbSNP Gene:1675 CFD

ENSEMBL:ENSG00000197766 CFD

ENSEMBL_homo_sapiens_GENE:ENSG00000197766.9 CFD

ENSEMBL_homo_sapiens_GENE:ENSG00000274619.2 CFD

HGNC:2771 CFD

KEGG Gene (Homo sapiens):1675 CFD

Monarch:1675 CFD

NCBI Gene:1675 CFD

OMIM:134350 CFD

UCSC:P00746 CFD

Reference Transcript

Other Identifiers

11725980_at

1675

16856299

205382_PM_s_at

205382_s_at

3815244

3815245

3815246

3815247

3815249

3815251

3815252

3815253

3815254

3815255

40282_s_at

8024062

A_14_P124724

A_23_P119562

GE81088

GO:0002376

GO:0003824

GO:0004252

GO:0005576

GO:0005615

GO:0006508

GO:0006956

GO:0006957

GO:0008233

GO:0008236

GO:0009617

GO:0016787

GO:0031093

GO:0031410

GO:0034774

GO:0043226

GO:0045087

GO:0070062

GO:0098542

GO:0140096

GO:1904813

HMNXSV003001420

ILMN_1777190

M84526_at

PH_hs_0029251

TC19000020.hg

g4503308_3p_at

Participates

as a member of

Other forms of this molecule

CFD [platelet alpha granule lumen]

CFD [secretory granule lumen]

CFD [ficolin-1-rich granule lumen]

Inferred To

CFD [extracellular region] (Bos taurus)

CFD [extracellular region] (Canis familiaris)

CFD [extracellular region] (Gallus gallus)

CFD [extracellular region] (Sus scrofa)

zgc:109940 [extracellular region] (Danio rerio)

Cfd [extracellular region] (Mus musculus)

Cfd [extracellular region] (Rattus norvegicus)

ami [extracellular region] (Xenopus tropicalis)

Cross References

RefSeq

NP_001304264.1, NP_001919.2

Guide to Pharmacology - Targets

2842

OpenTargets

ENSG00000197766

ZINC - Substances

CFAD_HUMAN

ZINC target

P00746

PRO

P00746

PDB

5NAR, 1DIC, 4CBN, 6FUG, 1HFD, 4D9R, 1BIO, 6QMR, 2XW9, 5FBI, 5NAT, 6FUH, 8DG6, 8D95, 6FUT, 1DSU, 6FTZ, 2XWB, 5NBA, 1DST, 4CBO, 2XWA, 1FDP, 5TCA, 6FUJ, 5FCK, 5NB7, 6FTY, 5MT4, 5TCC, 6QMT, 8DEA, 6VMJ, 5FBE, 5NAW, 6FUI, 5NB6, 5MT0, 1DFP, 6VMK

HPA

ENSG00000197766-CFD

GeneCards

P00746

Ensembl

ENSP00000332139, ENST00000327726, ENSP00000478745, ENSG00000197766, ENST00000617994, ENSG00000274619

Pharos - Targets

P00746

Orphanet

18958

ZINC - Predictions - Purchasable

CFAD_HUMAN