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glc-fuc-ADAMTS14 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-5173268
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
O-fuc-ADAMTS14, ADAMTS14, A disintegrin and metalloproteinase with thrombospondin motifs 14, ATS14_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-glycosylation of TSR domain-containing proteins (Homo sapiens)
B3GALTL transfers glucose to O-fucosyl-proteins (Homo sapiens)
glc-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
glc-fuc-ADAMTS14 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8WXS8 ADAMTS14
Gene Names
ADAMTS14
Chain
signal peptide:1-22, propeptide:23-252, chain:253-1223
Reference Genes
BioGPS Gene:140766 ADAMTS14
COSMIC (genes):ADAMTS14 ADAMTS14
CTD Gene:140766 ADAMTS14
dbSNP Gene:140766 ADAMTS14
ENSEMBL:ENSG00000138316 ADAMTS14
ENSEMBL_homo_sapiens_GENE:ENSG00000138316.11 ADAMTS14
HGNC:14899 ADAMTS14
KEGG Gene (Homo sapiens):140766 ADAMTS14
Monarch:140766 ADAMTS14
NCBI Gene:140766 ADAMTS14
OMIM:607506 ADAMTS14
UCSC:Q8WXS8 ADAMTS14
Reference Transcript
RefSeq:NM_139155.3 ADAMTS14
RefSeq:NM_080722.4 ADAMTS14
Other Identifiers
11726953_at
11726954_at
140766
16705754
230167_PM_at
230167_at
3250807
3250809
3250810
3250811
3250819
3250823
3250827
3250828
3250830
3250831
3250833
3250835
3250836
3250837
3250838
3250839
3250840
3250842
3250846
3250848
3250849
3250850
3250851
3250852
3250853
3250854
3250855
3250856
3250858
3250860
61932_at
7928147
A_23_P202558
GE86913
GO:0003824
GO:0004222
GO:0005576
GO:0006508
GO:0008233
GO:0008237
GO:0016787
GO:0030198
GO:0030199
GO:0030312
GO:0030574
GO:0031012
GO:0046872
GO:0140096
HMNXSV003012121
Hs.135255.0.A1_3p_at
Hs.135255.0.A1_3p_x_at
ILMN_1676452
ILMN_2358134
PH_hs_0017037
TC10000433.hg
Participates
as a candidate of
glc-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
ADAMTS14 [extracellular region]
ADAMTS14 [endoplasmic reticulum lumen]
O-fuc-ADAMTS14 [endoplasmic reticulum lumen]
Inferred To
rsc22 [endoplasmic reticulum lumen]
(Dictyostelium discoideum)
glc-fuc-ADAMTS14 [endoplasmic reticulum lumen]
(Bos taurus)
glc-fuc-ADAMTS14 [endoplasmic reticulum lumen]
(Canis familiaris)
glc-fuc-ADAMTS14 [endoplasmic reticulum lumen]
(Gallus gallus)
glc-fuc-ADAMTS14 [endoplasmic reticulum lumen]
(Mus musculus)
glc-fuc-ADAMTS14 [endoplasmic reticulum lumen]
(Rattus norvegicus)
glc-fuc-ADAMTS14 [endoplasmic reticulum lumen]
(Sus scrofa)
glc-fuc-ADAMTS14 [endoplasmic reticulum lumen]
(Xenopus tropicalis)
Modified Residues
Name
O-fucosyl-L-serine (ChEBI:76521) at unknown position
Modification
beta-D-glucosyl-(1->3)-alpha-L-fucosyl group
PsiMod Name
O-fucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to an O-fucosylserine.
Cross References
RefSeq
NP_542453.2
,
NP_631894.2
Guide to Pharmacology - Targets
1686
OpenTargets
ENSG00000138316
HPA
ENSG00000138316-ADAMTS14
GeneCards
Q8WXS8
Ensembl
ENSG00000138316
,
ENSP00000362303
,
ENST00000373208
,
ENST00000373207
,
ENSP00000362304
PRO
Q8WXS8
Pharos - Targets
Q8WXS8
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