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O-fuc-SPON1 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-5173232
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
SPON1, Spondin-1, SPON1_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with O-glycosylation of proteins (Homo sapiens)
Defective B3GALTL causes PpS (Homo sapiens)
Defective B3GALTL does not transfer glucose to O-fucosyl-proteins (Homo sapiens)
O-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
O-fuc-SPON1 [endoplasmic reticulum lumen] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-glycosylation of TSR domain-containing proteins (Homo sapiens)
B3GALTL transfers glucose to O-fucosyl-proteins (Homo sapiens)
O-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
O-fuc-SPON1 [endoplasmic reticulum lumen] (Homo sapiens)
POFUT2 transfers fucose to TSR domain-containing proteins (Homo sapiens)
O-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
O-fuc-SPON1 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9HCB6 SPON1
Gene Names
SPON1, KIAA0762, VSGP
Chain
signal peptide:1-28, chain:29-807
Reference Genes
BioGPS Gene:10418 SPON1
COSMIC (genes):SPON1 SPON1
CTD Gene:10418 SPON1
dbSNP Gene:10418 SPON1
ENSEMBL:ENSG00000262655 SPON1
HGNC:11252 SPON1
Monarch:10418 SPON1
NCBI Gene:10418 SPON1
OMIM:604989 SPON1
UCSC:Q9HCB6 SPON1
Reference Transcript
RefSeq:NM_006108.3 SPON1
Other Identifiers
10418
11724501_at
11724502_at
11724503_at
11724504_at
16722278
209436_PM_at
209436_at
209437_PM_s_at
209437_s_at
213993_PM_at
213993_at
213994_PM_s_at
213994_s_at
224488_PM_s_at
224488_s_at
3321362
3321363
3321375
3321384
3321392
3321393
3321394
3321406
3321427
3321429
3321430
3321432
3321434
3321435
3321436
3321438
3321440
3321441
3321442
3321443
3321444
3321445
3321446
35277_at
7938608
A_14_P112513
A_14_P138203
A_32_P133072
GE53470
GE83492
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005615
GO:0005788
GO:0007155
GO:0010954
GO:0016485
GO:0030312
GO:0031012
GO:0046872
GO:0050693
GO:0051604
GO:0062023
GO:1902430
GO:1902993
HMNXSV003032361
Hs.5378.0.S2_3p_a_at
Hs.5378.0.S2_3p_x_at
Hs.5378.1.S1_3p_at
ILMN_1791890
PH_hs_0000554
TC11000211.hg
g11320819_3p_a_at
p2660
Participates
as a member of
O-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
SPON1 [endoplasmic reticulum lumen]
glc-fuc-SPON1 [endoplasmic reticulum lumen]
Inferred To
spon-1 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
SPON1 [endoplasmic reticulum lumen]
(Canis familiaris)
spon1 [endoplasmic reticulum lumen]
(Xenopus tropicalis)
O-fuc-SPON1 [endoplasmic reticulum lumen]
(Bos taurus)
O-fuc-SPON1 [endoplasmic reticulum lumen]
(Gallus gallus)
O-fuc-SPON1 [endoplasmic reticulum lumen]
(Mus musculus)
O-fuc-SPON1 [endoplasmic reticulum lumen]
(Plasmodium falciparum)
O-fuc-SPON1 [endoplasmic reticulum lumen]
(Rattus norvegicus)
O-fuc-SPON1 [endoplasmic reticulum lumen]
(Sus scrofa)
spon1a [endoplasmic reticulum lumen]
(Danio rerio)
Dmel\CG17739 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
Modified Residues
Name
O-fucosyl-L-serine at unknown position
PsiMod Name
O-fucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to an O-fucosylserine.
Cross References
ENSEMBL
ENST00000576479
,
ENSP00000460236
OpenTargets
ENSG00000262655
HPA
ENSG00000262655-SPON1
PRO
Q9HCB6
Pharos - Targets
Q9HCB6
GlyGen
Q9HCB6
PDB
3Q13
,
2ZOU
,
3COO
,
2ZOT
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