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O-fuc-SEMA5A [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-5173149
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
SEMA5A, Semaphorin 5A, SM5A_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with O-glycosylation of proteins (Homo sapiens)
Defective B3GALTL causes PpS (Homo sapiens)
Defective B3GALTL does not transfer glucose to O-fucosyl-proteins (Homo sapiens)
O-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
O-fuc-SEMA5A [endoplasmic reticulum lumen] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-glycosylation of TSR domain-containing proteins (Homo sapiens)
B3GALTL transfers glucose to O-fucosyl-proteins (Homo sapiens)
O-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
O-fuc-SEMA5A [endoplasmic reticulum lumen] (Homo sapiens)
POFUT2 transfers fucose to TSR domain-containing proteins (Homo sapiens)
O-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
O-fuc-SEMA5A [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13591 SEMA5A
Gene Names
SEMA5A, SEMAF
Chain
signal peptide:1-22, chain:23-1074
Reference Genes
BioGPS Gene:9037 SEMA5A
COSMIC (genes):SEMA5A SEMA5A
CTD Gene:9037 SEMA5A
dbSNP Gene:9037 SEMA5A
ENSEMBL:ENSG00000112902 SEMA5A
ENSEMBL_homo_sapiens_GENE:ENSG00000112902.12 SEMA5A
HGNC:10736 SEMA5A
KEGG Gene (Homo sapiens):9037 SEMA5A
Monarch:9037 SEMA5A
NCBI Gene:9037 SEMA5A
OMIM:609297 SEMA5A
Reference Transcript
RefSeq:XM_011514157.1 SEMA5A
RefSeq:XM_006714506.2 SEMA5A
RefSeq:XM_011514156.1 SEMA5A
RefSeq:NM_003966.2 SEMA5A
RefSeq:XM_011514158.1 SEMA5A
RefSeq:XM_011514155.2 SEMA5A
RefSeq:XM_006714507.3 SEMA5A
Other Identifiers
11719518_at
11719519_at
11719520_at
11719521_at
11719522_at
16994272
205405_PM_at
205405_at
213169_PM_at
213169_at
229427_PM_at
229427_at
2847973
2847974
2847975
2847976
2847977
2847978
2847979
2847980
2847981
2847983
2847987
2847988
2847989
2847990
2847991
2847996
2847997
2848011
2848012
2848021
2848022
2848024
2848029
2848031
2848041
2848043
2848044
2848050
2848051
2848052
2848064
2848067
2848077
2848078
2848079
2848083
2848088
35204_at
36061_at
55406_at
63084_s_at
8110932
9037
A_23_P213415
A_24_P912799
A_33_P3372727
GE54097
GE61478
GO:0001755
GO:0001938
GO:0002043
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0007010
GO:0007155
GO:0007162
GO:0007267
GO:0007399
GO:0007411
GO:0007413
GO:0012501
GO:0016020
GO:0021536
GO:0023052
GO:0030154
GO:0030215
GO:0030335
GO:0030836
GO:0035373
GO:0043226
GO:0043395
GO:0045499
GO:0045545
GO:0045766
GO:0048018
GO:0048675
GO:0048842
GO:0048843
GO:0048856
GO:0048870
GO:0050918
GO:0050919
GO:0051897
GO:0060326
GO:0070062
GO:0071526
GO:0090263
GO:0098772
GO:1990256
GO:2000352
GO:2001028
HMNXSV003054213
Hs.49476.0.S1_3p_at
Hs.89319.0.A1_3p_at
ILMN_1880012
PH_hs_0002445
TC05001151.hg
TC05002857.hg
U52840_at
g4506880_3p_x_at
Participates
as a candidate of
O-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
SEMA5A [endoplasmic reticulum lumen]
glc-fuc-SEMA5A [endoplasmic reticulum lumen]
SEMA5A [plasma membrane]
Inferred To
SEMA5A [endoplasmic reticulum lumen]
(Bos taurus)
SEMA5A [endoplasmic reticulum lumen]
(Canis familiaris)
SEMA5A [endoplasmic reticulum lumen]
(Gallus gallus)
SEMA5A [endoplasmic reticulum lumen]
(Sus scrofa)
Sema5a [endoplasmic reticulum lumen]
(Mus musculus)
Sema5a [endoplasmic reticulum lumen]
(Rattus norvegicus)
Sema5c [endoplasmic reticulum lumen]
(Drosophila melanogaster)
sema5a [endoplasmic reticulum lumen]
(Danio rerio)
Modified Residues
Name
O-fucosyl-L-serine at unknown position
PsiMod Name
O-fucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to an O-fucosylserine.
Cross References
RefSeq
XP_011512460.1
,
XP_006714569.1
,
XP_011512457.1
,
NP_003957.2
,
XP_006714570.1
,
XP_011512459.1
,
XP_011512458.1
OpenTargets
ENSG00000112902
HPA
ENSG00000112902-SEMA5A
GeneCards
Q13591
Ensembl
ENSP00000499013
,
ENSG00000112902
,
ENSP00000371936
,
ENST00000382496
,
ENST00000652226
PRO
Q13591
Pharos - Targets
Q13591
Orphanet
17200
PDB
8CKK
,
8CKL
,
8CKM
,
8CKG
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