Reactome | glc-fuc-CFP [endoplasmic reticulum lumen]

glc-fuc-CFP [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-5173137

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

O-fuc-CFP, CFP, Properdin

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P27918 CFP

Gene Names

CFP, PFC

Chain

signal peptide:1-27, chain:28-469

Reference Genes

BioGPS Gene:5199 CFP

COSMIC (genes):CFP CFP

CTD Gene:5199 CFP

dbSNP Gene:5199 CFP

ENSEMBL:ENSG00000126759 CFP

HGNC:8864 CFP

KEGG Gene (Homo sapiens):5199 CFP

Monarch:5199 CFP

NCBI Gene:5199 CFP

OMIM:300383 CFP

UCSC:P27918 CFP

Reference Transcript

Other Identifiers

11727118_a_at

17110463

206380_s_at

39997_at

4007163

4007165

4007166

4007168

4007170

4007172

4007173

4007174

4007175

4007176

4007178

4007179

4007180

4007181

4007182

4007183

5199

8172333

A_23_P22444

GE54066

GO:0002376

GO:0003674

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005783

GO:0005788

GO:0006810

GO:0006950

GO:0006955

GO:0006956

GO:0006957

GO:0008150

GO:0016192

GO:0030141

GO:0030449

GO:0031012

GO:0031410

GO:0035580

GO:0042742

GO:0043226

GO:0043312

GO:0045087

GO:0062023

GO:1904724

HMNXSV003054370

M83652_s_at

PH_hs_0003542

TC0X000998.hg

g4505736_3p_a_at

Participates

as a member of

glc-fuc-proteins [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

CFP [extracellular region]

CFP [tertiary granule lumen]

CFP [specific granule lumen]

O-fuc-CFP [endoplasmic reticulum lumen]

CFP [endoplasmic reticulum lumen]

Inferred To

Cfp [endoplasmic reticulum lumen] (Mus musculus)

Cfp [endoplasmic reticulum lumen] (Rattus norvegicus)

si:ch73-237c6.1 [endoplasmic reticulum lumen] (Danio rerio)

Homologues of glc-fuc-CFP [endoplasmic reticulum lumen] (Caenorhabditis elegans)

glc-fuc-CFP [endoplasmic reticulum lumen] (Caenorhabditis elegans)

CFP [endoplasmic reticulum lumen] (Bos taurus)

CFP [endoplasmic reticulum lumen] (Canis familiaris)

CFP [endoplasmic reticulum lumen] (Sus scrofa)

Modified Residues

Name

O-fucosyl-L-serine (ChEBI:76521) at unknown position

Modification

beta-D-glucosyl-(1->3)-alpha-L-fucosyl group

PsiMod Name

O-fucosyl-L-serine

PsiMod Definition

A protein modification that effectively converts an L-serine residue to an O-fucosylserine.

Cross References

RefSeq

NP_002612.1, NP_001138724.1

OpenTargets

ENSG00000126759

GeneCards

P27918

HPA

ENSG00000126759-CFP

Ensembl

ENST00000247153, ENSP00000380189, ENST00000396992, ENSP00000247153, ENSG00000126759

PRO

P27918

Pharos - Targets

P27918

Orphanet

15440

GlyGen

P27918

PDB

6RUR, 6SEJ, 1W0R, 6S0A, 1W0S, 6RUS, 6RV6, 6S08, 6RUV, 6S0B

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75344 FKBP6	2	FKBP6 [nucleoplasm] (R-HSA-912512) FKBP6 [cytosol] (R-HSA-5601923)	0.601	4
UniProt:O95231 VENTX	1	VENTX [nucleoplasm] (R-HSA-8853887)	0.556	5
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3