ATF7IP binds SETDB1

Stable Identifier
R-HSA-5159250
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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ATF7IP binds SETDB1
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SETDB1 (ESET, KMT1E) is one of several protein lysine methyltransferases which selectively methylate lysine-10 of the amino terminus of histone H3 (H3K9) (Rea et al. 2000). It is most effective when complexed with ATF7IP (MCAF, hAM) (Wang et al. 2003).
Literature References
PubMed ID Title Journal Year
14536086 mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression

Roeder, RG, An, W, Chatton, B, Zhang, Y, Xia, L, Wang, H, Tempst, P, Cao, R, Erdjument-Bromage, H

Mol. Cell 2003
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Orthologous Events
ATF7IP binds SETDB1 (Bos taurus)
ATF7IP binds SETDB1 (Canis familiaris)
ATF7IP binds SETDB1 (Danio rerio)
ATF7IP binds SETDB1 (Drosophila melanogaster)
ATF7IP binds SETDB1 (Gallus gallus)
ATF7IP binds SETDB1 (Mus musculus)
ATF7IP binds SETDB1 (Rattus norvegicus)
ATF7IP binds SETDB1 (Sus scrofa)
Authored
Jupe, S  (2013-03-12)
Reviewed
Motamedi, M  (2014-11-17)
Created
Jupe, S  (2013-11-22)
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