Reactome | GMPR2 [cytosol]

GMPR2 [cytosol]

Stable Identifier

R-HSA-514631

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

GMP reductase 2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9P2T1 GMPR2

Gene Names

GMPR2

Chain

chain:1-348

Reference Genes

BioGPS Gene:51292 GMPR2

COSMIC (genes):GMPR2 GMPR2

CTD Gene:51292 GMPR2

dbSNP Gene:51292 GMPR2

ENSEMBL:ENSG00000100938 GMPR2

HGNC:4377 GMPR2

KEGG:hsa:51292 GMPR2

Monarch:51292 GMPR2

NCBI Gene:51292 GMPR2

OMIM:610781 GMPR2

UCSC:Q9P2T1 GMPR2

Reference Transcript

Other Identifiers

11725405_a_at

16782754

217990_PM_at

217990_at

3529800

3529801

3529802

3529803

3529804

3529805

3529807

3529808

3529809

3529810

3529811

3529812

3529813

3529814

3529815

3529816

3529817

3529818

3529819

3529820

3529821

3529822

3529823

3529824

3529825

3529826

3529827

3529828

3529829

3529830

3529831

3529832

3529833

51292

58784_s_at

66105_s_at

7973660

A_14_P111088

A_14_P128789

A_14_P137380

A_23_P3169

A_24_P56467

A_33_P3364459

GE62808

GO:0003824

GO:0003920

GO:0003938

GO:0005515

GO:0005829

GO:0006144

GO:0006163

GO:0006164

GO:0009117

GO:0016491

GO:0046037

GO:0046872

GO:0055086

GO:1901135

GO:1902560

HMNXSV003014215

ILMN_1677919

ILMN_1754788

ILMN_2365595

PH_hs_0024084

PH_hs_0038932

TC14000165.hg

g7706108_3p_at

g7706108_3p_x_at

Participates

as a component of

GMPR2 tetramer [cytosol] (Homo sapiens)

Inferred To

GMPR2 [cytosol] (Bos taurus)

GMPR2 [cytosol] (Caenorhabditis elegans)

GMPR2 [cytosol] (Canis familiaris)

GMPR2 [cytosol] (Danio rerio)

GMPR2 [cytosol] (Mus musculus)

GMPR2 [cytosol] (Rattus norvegicus)

GMPR2 [cytosol] (Sus scrofa)

GMPR2 [cytosol] (Xenopus tropicalis)

Cross References

OpenTargets

ENSG00000100938

ENSEMBL

ENST00000642276, ENSP00000392859, ENSP00000494224, ENST00000456667, ENSP00000382369, ENSP00000495708, ENSP00000347449, ENSP00000496504, ENST00000643803, ENST00000355299, ENST00000399440, ENSP00000453299, ENSP00000495583, ENST00000647320, ENSP00000405743, ENST00000644066, ENSP00000496234, ENST00000559836, ENST00000645781, ENST00000420554

HPA

ENSG00000100938-GMPR2

PRO

Q9P2T1

Pharos - Targets

Q9P2T1

GlyGen

Q9P2T1

PDB

2C6Q, 2BZN, 2A7R

HMDB Protein

HMDBP00678

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04626 ERBB2	20	ERBB2 G309E [plasma membrane] (R-HSA-9665342) ERBB2 G309A [plasma membrane] (R-HSA-9665349) ERBB2 S310F [plasma membrane] (R-HSA-9665350) ERBB2 S310Y [plasma membrane] (R-HSA-9665344) p-6Y-ERBB2 G309A [plasma membrane] (R-HSA-9665381) p-6Y-ERBB2 G309E [plasma membrane] (R-HSA-9665382) p-6Y-ERBB2 S310F [plasma membrane] (R-HSA-9665379) p-6Y-ERBB2 S310Y [plasma membrane] (R-HSA-9665385) p-Y-ERBB2 L755P [plasma membrane] (R-HSA-9654268) p-Y-ERBB2 I767M [plasma membrane] (R-HSA-9654303) p-Y-ERBB2 T798I [plasma membrane] (R-HSA-9654618) p-Y-ERBB2 Y772_A775dup [plasma membrane] (R-HSA-9665652) p-Y-ERBB2 T862A [plasma membrane] (R-HSA-9654695) p-Y-ERBB2 T798M [plasma membrane] (R-HSA-9654615) p-Y-ERBB2 H878Y [plasma membrane] (R-HSA-9654833) p-Y-ERBB2 V777L [plasma membrane] (R-HSA-9654401) p-Y-ERBB2 L755S [plasma membrane] (R-HSA-9654194) p-Y-ERBB2 V777E [plasma membrane] (R-HSA-9654397) p-Y-ERBB2 V777M [plasma membrane] (R-HSA-9654398) p-Y-ERBB2 L755M [plasma membrane] (R-HSA-9654191)	0.553	2

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