WNT5A-FZD4 recruits DVL2

Stable Identifier
R-HSA-5138441
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, cytosol, extracellular region
ReviewStatus
5/5
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WNT5A-FZD4 recruits DVL2
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DVL2 is recruited to the WNT5A:FZD4 receptor complex as assessed by co-localization and co-immunoprecipitation (Chen et al, 2003).
Literature References
PubMed ID Title Journal Year
12958364 Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4

Chen, W, Ahn, S, Caron, MG, Barak, LS, Brown, J, Hu, LA, Lefkowitz, RJ, Nusse, R, Miller, WE, ten Berge, D

Science 2003
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Output
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Orthologous Events
WNT5A-FZD4 recruits DVL2 (Bos taurus)
WNT5A-FZD4 recruits DVL2 (Caenorhabditis elegans)
WNT5A-FZD4 recruits DVL2 (Canis familiaris)
WNT5A-FZD4 recruits DVL2 (Mus musculus)
WNT5A-FZD4 recruits DVL2 (Rattus norvegicus)
WNT5A-FZD4 recruits DVL2 (Sus scrofa)
WNT5A-FZD4 recruits DVL2 (Xenopus tropicalis)
Authored
Kikuchi, A  (2013-11-13)
Created
Rothfels, K  (2013-11-15)
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