Reactome | clathrin:AP-2 [plasma membrane]

clathrin:AP-2 [plasma membrane]

Stable Identifier

R-HSA-5138434

Type

Complex

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

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Participants

components

Participates

as an input of

p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Homo sapiens)

as a component of

WNT5A:FZD4:p-DVL2:ARRB2:AP-2:clathrin [plasma membrane] (Homo sapiens)

This entity regulates

Positively

FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Homo sapiens)

Inferred To

clathrin:AP-2 [plasma membrane] (Bos taurus)

clathrin:AP-2 [plasma membrane] (Caenorhabditis elegans)

clathrin:AP-2 [plasma membrane] (Canis familiaris)

clathrin:AP-2 [plasma membrane] (Drosophila melanogaster)

clathrin:AP-2 [plasma membrane] (Gallus gallus)

clathrin:AP-2 [plasma membrane] (Mus musculus)

clathrin:AP-2 [plasma membrane] (Rattus norvegicus)

clathrin:AP-2 [plasma membrane] (Sus scrofa)

clathrin:AP-2 [plasma membrane] (Xenopus tropicalis)

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