WNT5A binds FZD4

Stable Identifier
R-HSA-5099899
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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WNT5A stimulation of FZD4-expressing HEK293 cells promotes internalization of the receptor, suggesting a receptor-ligand interaction (Chen et al, 2003).

Literature References
PubMed ID Title Journal Year
12958364 Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4

Chen, W, ten Berge, D, Brown, J, Ahn, S, Hu, LA, Miller, WE, Caron, MG, Barak, LS, Nusse, R, Lefkowitz, RJ

Science 2003
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