Reactome | MTF2 [nucleoplasm]

MTF2 [nucleoplasm]

Stable Identifier

R-HSA-5084119

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Metal-response element-binding transcription factor 2, MTF2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y483 MTF2

Gene Names

MTF2, PCL2

Chain

chain:1-593

Reference Genes

BioGPS Gene:22823 MTF2

COSMIC (genes):MTF2 MTF2

CTD Gene:22823 MTF2

dbSNP Gene:22823 MTF2

ENSEMBL:ENSG00000143033 MTF2

HGNC:29535 MTF2

KEGG:hsa:22823 MTF2

Monarch:22823 MTF2

NCBI Gene:22823 MTF2

OMIM:609882 MTF2

UCSC:Q9Y483 MTF2

Reference Transcript

Participates

as a component of

PRC2:JARID2:MTF2 [nucleoplasm] (Homo sapiens)

Inferred To

mtf2 [nucleoplasm] (Danio rerio)

MTF2 [nucleoplasm] (Bos taurus)

MTF2 [nucleoplasm] (Canis familiaris)

MTF2 [nucleoplasm] (Gallus gallus)

MTF2 [nucleoplasm] (Sus scrofa)

Ghost homologue of MTF2 [nucleoplasm] (Drosophila melanogaster)

Mtf2 [nucleoplasm] (Mus musculus)

Mtf2 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_031384.1, XP_016856165.1, NP_001157865.1, NP_001157863.1, NP_001157864.1, XP_011539318.1

ENSEMBL

ENST00000545708, ENST00000370303, ENSG00000143033, ENST00000540243, ENSP00000444962, ENSP00000359326, ENSP00000359321, ENST00000370298, ENSP00000443295

OpenTargets

ENSG00000143033

GeneCards

MTF2

HPA

ENSG00000143033-MTF2

PRO

Q9Y483

Pharos - Targets

Q9Y483

PDB

5XFR

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15910 EZH2	1	EZH2 [nucleoplasm] (R-HSA-212298)	0.788	6
UniProt:Q16576 RBBP7	1	RBBP7 [nucleoplasm] (R-HSA-212227)	0.788	8
UniProt:Q15022 SUZ12	2	SUZ12 [nucleoplasm] (R-HSA-212217) monoSUMO1-K75-SUZ12 [nucleoplasm] (R-HSA-4615932)	0.725	6
UniProt:Q09028 RBBP4	1	RBBP4 [nucleoplasm] (R-HSA-212223)	0.725	5
UniProt:O75530 EED	1	EED [nucleoplasm] (R-HSA-212278)	0.643	4

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