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p-S326-HSF1 trimer [nucleoplasm]
Stable Identifier
R-HSA-5082354
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to heat stress (Homo sapiens)
HSF1-dependent transactivation (Homo sapiens)
HSF1-mediated gene expression (Homo sapiens)
p-S326-HSF1 trimer [nucleoplasm] (Homo sapiens)
Phosphorylation of HSF1 at Ser326 induces transactivation (Homo sapiens)
p-S326-HSF1 trimer [nucleoplasm] (Homo sapiens)
Mitochondrial unfolded protein response (UPRmt) (Homo sapiens)
ATF5 and HSF1 trimer activate expression of HSPA9 (mtHSP70) (Homo sapiens)
ATF5:HSF1 trimer:HSPA9 gene [nucleoplasm] (Homo sapiens)
p-S326-HSF1 trimer [nucleoplasm] (Homo sapiens)
p-S326-HSF1 trimer [nucleoplasm] (Homo sapiens)
ATF5 and HSF1 trimer activate expression of HSPD1 (Homo sapiens)
ATF5:HSF1 trimer:HSPD1 gene:HSPE1 gene [nucleoplasm] (Homo sapiens)
p-S326-HSF1 trimer [nucleoplasm] (Homo sapiens)
ATF5 and HSF1 trimer activate expression of HSPE1 (Homo sapiens)
ATF5:HSF1 trimer:HSPD1 gene:HSPE1 gene [nucleoplasm] (Homo sapiens)
p-S326-HSF1 trimer [nucleoplasm] (Homo sapiens)
ATF5 and HSF1 trimer bind the HSPA9 gene (Homo sapiens)
ATF5:HSF1 trimer:HSPA9 gene [nucleoplasm] (Homo sapiens)
p-S326-HSF1 trimer [nucleoplasm] (Homo sapiens)
p-S326-HSF1 trimer [nucleoplasm] (Homo sapiens)
ATF5 and HSF1 trimer bind the bidirectional promoter of the HSPD1 gene and HSPE1 gene (Homo sapiens)
ATF5:HSF1 trimer:HSPD1 gene:HSPE1 gene [nucleoplasm] (Homo sapiens)
p-S326-HSF1 trimer [nucleoplasm] (Homo sapiens)
p-S326-HSF1 trimer [nucleoplasm] (Homo sapiens)
HSF1 is activated by phosphorylation, translocation to the nucleus, and trimerization (Homo sapiens)
p-S326-HSF1 trimer [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
8114740
Human heat shock factors 1 and 2 are differentially activated and can synergistically induce hsp70 gene transcription
Sistonen, L
,
Morimoto, RI
,
Sarge, KD
Mol. Cell. Biol.
1994
Participants
components
x 3
p-S326-hC36,103-HSF1 [nucleoplasm]
(Homo sapiens)
Participates
as an output of
Phosphorylation of HSF1 at Ser326 induces transactivation (Homo sapiens)
HSF1 is activated by phosphorylation, translocation to the nucleus, and trimerization (Homo sapiens)
as an input of
ATF5 and HSF1 trimer bind the bidirectional promoter of the HSPD1 gene and HSPE1 gene (Homo sapiens)
ATF5 and HSF1 trimer bind the HSPA9 gene (Homo sapiens)
as a component of
ATF5:HSF1 trimer:HSPD1 gene:HSPE1 gene [nucleoplasm] (Homo sapiens)
ATF5:HSF1 trimer:HSPA9 gene [nucleoplasm] (Homo sapiens)
This entity regulates
Positively
HSF1-mediated gene expression
(Homo sapiens)
Inferred To
p-S326-HSF1 trimer [nucleoplasm]
(Bos taurus)
p-S326-HSF1 trimer [nucleoplasm]
(Caenorhabditis elegans)
p-S326-HSF1 trimer [nucleoplasm]
(Canis familiaris)
p-S326-HSF1 trimer [nucleoplasm]
(Dictyostelium discoideum)
p-S326-HSF1 trimer [nucleoplasm]
(Drosophila melanogaster)
p-S326-HSF1 trimer [nucleoplasm]
(Gallus gallus)
p-S326-HSF1 trimer [nucleoplasm]
(Mus musculus)
p-S326-HSF1 trimer [nucleoplasm]
(Rattus norvegicus)
p-S326-HSF1 trimer [nucleoplasm]
(Saccharomyces cerevisiae)
p-S326-HSF1 trimer [nucleoplasm]
(Schizosaccharomyces pombe)
p-S326-HSF1 trimer [nucleoplasm]
(Sus scrofa)
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