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CHRNE [plasma membrane]
Stable Identifier
R-HSA-507845
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Acetylcholine receptor subunit epsilon, ACHE_HUMAN
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Acetylcholine binding and downstream events (Homo sapiens)
Postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Homo sapiens)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
CHRNE [plasma membrane] (Homo sapiens)
Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
CHRNE [plasma membrane] (Homo sapiens)
O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
CHRNE [plasma membrane] (Homo sapiens)
Presynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Homo sapiens)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
CHRNE [plasma membrane] (Homo sapiens)
Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
CHRNE [plasma membrane] (Homo sapiens)
O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
CHRNE [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q04844 CHRNE
Gene Names
CHRNE, ACHRE
Chain
signal peptide:1-20, chain:21-493
Reference Genes
BioGPS Gene:1145 CHRNE
COSMIC (genes):CHRNE CHRNE
CTD Gene:1145 CHRNE
dbSNP Gene:1145 CHRNE
ENSEMBL:ENSG00000108556.10 CHRNE
HGNC:1966 CHRNE
KEGG Gene (Homo sapiens):1145 CHRNE
Monarch:1145 CHRNE
NCBI Gene:1145 CHRNE
OMIM:100725 CHRNE
UCSC:Q04844 CHRNE
Reference Transcript
RefSeq:NM_000080.3 CHRNE
Other Identifiers
0006620520
1145
11735601_at
16840131
207274_PM_at
207274_at
3742352
3742353
3742354
3742355
3742356
3742357
3742358
3742360
3742361
3742362
3742365
3742367
3742368
3742369
3742370
3742371
39834_at
8011734
A_23_P304279
GE80887
GO:0003012
GO:0004888
GO:0005215
GO:0005216
GO:0005230
GO:0005231
GO:0005886
GO:0005887
GO:0005892
GO:0006811
GO:0006936
GO:0007165
GO:0007268
GO:0007271
GO:0008324
GO:0015464
GO:0016020
GO:0016021
GO:0022848
GO:0023052
GO:0030594
GO:0031594
GO:0032991
GO:0034220
GO:0042391
GO:0043005
GO:0045202
GO:0045211
GO:0050877
GO:0055085
GO:0060078
GO:0060079
GO:0060089
GO:0098655
GO:0110165
GO:1904315
HMNXSV003050423
ILMN_1703346
PH_hs_0015915
TC17001032.hg
X66403_at
g4557462_3p_at
g4557462_3p_x_at
Participates
as a member of
Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
Inferred To
acr-12 [plasma membrane]
(Caenorhabditis elegans)
unc-63 [plasma membrane]
(Caenorhabditis elegans)
lev-1 [plasma membrane]
(Caenorhabditis elegans)
nAChRalpha3 [plasma membrane]
(Drosophila melanogaster)
lgc-27 [plasma membrane]
(Caenorhabditis elegans)
nAChRalpha4 [plasma membrane]
(Drosophila melanogaster)
acr-6 [plasma membrane]
(Caenorhabditis elegans)
nAChRbeta2 [plasma membrane]
(Drosophila melanogaster)
acr-2 [plasma membrane]
(Caenorhabditis elegans)
lgc-21 [plasma membrane]
(Caenorhabditis elegans)
nAChRbeta3 [plasma membrane]
(Drosophila melanogaster)
chrne [plasma membrane]
(Xenopus tropicalis)
nAChRalpha1 [plasma membrane]
(Drosophila melanogaster)
unc-38 [plasma membrane]
(Caenorhabditis elegans)
acr-8 [plasma membrane]
(Caenorhabditis elegans)
nAChRalpha2 [plasma membrane]
(Drosophila melanogaster)
unc-29 [plasma membrane]
(Caenorhabditis elegans)
CHRNE [plasma membrane]
(Bos taurus)
CHRNE [plasma membrane]
(Canis familiaris)
CHRNE [plasma membrane]
(Danio rerio)
acr-3 [plasma membrane]
(Caenorhabditis elegans)
Homologues of CHRNE [plasma membrane]
(Caenorhabditis elegans)
Homologues of CHRNE [plasma membrane]
(Drosophila melanogaster)
Chrne [plasma membrane]
(Mus musculus)
Chrne [plasma membrane]
(Rattus norvegicus)
lev-8 [plasma membrane]
(Caenorhabditis elegans)
lgc-33 [plasma membrane]
(Caenorhabditis elegans)
nAChRbeta1 [plasma membrane]
(Drosophila melanogaster)
lgc-20 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_000071.1
ZINC - World Drugs
ACHE_HUMAN
Guide to Pharmacology - Targets
477
OpenTargets
ENSG00000108556
ZINC - Substances
ACHE_HUMAN
ZINC target
Q04844
PRO
Q04844
HPA
ENSG00000108556-CHRNE
GeneCards
Q04844
Ensembl
ENSP00000497829
,
ENSG00000108556
,
ENST00000649488
Pharos - Targets
Q04844
Orphanet
15451
ZINC - Predictions - Purchasable
ACHE_HUMAN
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