Reactome | CHRNG [plasma membrane]

CHRNG [plasma membrane]

Stable Identifier

R-HSA-507843

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Acetylcholine receptor subunit gamma, ACHG_HUMAN

Locations in the PathwayBrowser

Expand all

Neuronal System (Homo sapiens)

- Transmission across Chemical Synapses (Homo sapiens)
  - Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
    - Acetylcholine binding and downstream events (Homo sapiens)
      - Postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
        
        Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Homo sapiens)
        
        Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
        
        O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
        
        Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
        
        Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
        
        Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
        
        CHRNG [plasma membrane] (Homo sapiens)
        
        Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Homo sapiens)
        
        Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
        
        Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
        
        Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
        
        CHRNG [plasma membrane] (Homo sapiens)
        
        O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
        
        Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
        
        Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
        
        Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
        
        CHRNG [plasma membrane] (Homo sapiens)
      - Presynaptic nicotinic acetylcholine receptors (Homo sapiens)
        
        Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Homo sapiens)
        
        Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
        
        O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
        
        Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
        
        Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
        
        Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
        
        CHRNG [plasma membrane] (Homo sapiens)
        
        Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Homo sapiens)
        
        Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
        
        Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
        
        Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
        
        CHRNG [plasma membrane] (Homo sapiens)
        
        O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
        
        Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
        
        Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
        
        Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)
        
        CHRNG [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P07510 CHRNG

Gene Names

CHRNG, ACHRG

Chain

signal peptide:1-22, chain:23-517

Reference Genes

BioGPS Gene:1146 CHRNG

COSMIC (genes):CHRNG CHRNG

CTD Gene:1146 CHRNG

dbSNP Gene:1146 CHRNG

ENSEMBL:ENSG00000196811 CHRNG

HGNC:1967 CHRNG

KEGG Gene (Homo sapiens):1146 CHRNG

Monarch:1146 CHRNG

NCBI Gene:1146 CHRNG

OMIM:100730 CHRNG

UCSC:P07510 CHRNG

Reference Transcript

RefSeq:NM_005199.4 CHRNG

Other Identifiers

0004610592

1146

11742077_at

11752947_a_at

16892305

221355_at

2532400

2532401

2532403

2532404

2532405

2532406

2532407

2532408

2532409

2532411

2532412

2532413

2532414

2532415

2532416

2532417

2532418

2532419

2532421

2532423

8049166

A_23_P5718

A_33_P3212192

GE61002

GO:0003674

GO:0004888

GO:0005216

GO:0005230

GO:0005515

GO:0005575

GO:0005886

GO:0005887

GO:0006810

GO:0006811

GO:0006936

GO:0007165

GO:0007267

GO:0007268

GO:0007271

GO:0008150

GO:0015267

GO:0015464

GO:0016020

GO:0016021

GO:0022848

GO:0022857

GO:0030054

GO:0030594

GO:0034220

GO:0042391

GO:0043005

GO:0045202

GO:0045211

GO:0050877

GO:0055085

GO:0060078

GO:0060079

HMNXSV003010317

ILMN_1784633

PH_hs_0013145

TC02001403.hg

X01715_at

g7382453_3p_at

g7382453_3p_x_at

Participates

as a member of

Delta, epsilon, gamma subunits of acetylcholine receptor [plasma membrane] (Homo sapiens)

Inferred To

Homologues of CHRNG [plasma membrane] (Caenorhabditis elegans)

lgc-21 [plasma membrane] (Caenorhabditis elegans)

CHRNG [plasma membrane] (Canis familiaris)

CHRNG [plasma membrane] (Gallus gallus)

CHRNG [plasma membrane] (Xenopus tropicalis)

chrng [plasma membrane] (Danio rerio)

lgc-27 [plasma membrane] (Caenorhabditis elegans)

Chrng [plasma membrane] (Mus musculus)

Cross References

RefSeq

NP_005190.4

Guide to Pharmacology - Targets

475

OpenTargets

ENSG00000196811

GeneCards

P07510

HPA

ENSG00000196811-CHRNG

Ensembl

ENSP00000498757, ENSG00000196811, ENST00000651502, ENST00000389492, ENSP00000374143

PRO

P07510

Pharos - Targets

P07510

Orphanet

15452

GlyGen

P07510

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