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CHRNA7
Stable Identifier
R-HSA-507830
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Neuronal acetylcholine receptor subunit alpha-7, ACHA7_HUMAN
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Acetylcholine binding and downstream events (Homo sapiens)
Activation of Nicotinic Acetylcholine Receptors (Homo sapiens)
Postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor containing alpha7 subunit [plasma membrane] (Homo sapiens)
CHRNA7 [plasma membrane] (Homo sapiens)
acetylcholine receptor subunits [plasma membrane] (Homo sapiens)
CHRNA7 [plasma membrane] (Homo sapiens)
Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor containing alpha7 subunit [plasma membrane] (Homo sapiens)
CHRNA7 [plasma membrane] (Homo sapiens)
acetylcholine receptor subunits [plasma membrane] (Homo sapiens)
CHRNA7 [plasma membrane] (Homo sapiens)
O-acteylcholine bound to calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor containing alpha7 subunit [plasma membrane] (Homo sapiens)
CHRNA7 [plasma membrane] (Homo sapiens)
acetylcholine receptor subunits [plasma membrane] (Homo sapiens)
CHRNA7 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P36544 CHRNA7
Gene Names
CHRNA7, NACHRA7
Chain
signal peptide:1-22, chain:23-502
Reference Genes
BioGPS Gene:1139 CHRNA7
BioGPS Gene:89832 CHRNA7
COSMIC (genes):CHRNA7 CHRNA7
CTD Gene:1139 CHRNA7
CTD Gene:89832 CHRNA7
dbSNP Gene:1139 CHRNA7
dbSNP Gene:89832 CHRNA7
ENSEMBL:ENSG00000175344 CHRNA7
HGNC:1960 CHRNA7
KEGG Gene (Homo sapiens):hsa:1139 CHRNA7
Monarch:1139 CHRNA7
Monarch:89832 CHRNA7
NCBI Gene:1139 CHRNA7
NCBI Gene:89832 CHRNA7
OMIM:118511 CHRNA7
UCSC:P36544 CHRNA7
Reference Transcript
RefSeq:NM_148911.1 CHRNA7
RefSeq:NM_000746.5 CHRNA7
RefSeq:NM_001190455.2 CHRNA7
RefSeq:XM_017021884.1 CHRNA7
RefSeq:XM_005254750.2 CHRNA7
Other Identifiers
0004210114
0006040114
101929970
1139
11739850_s_at
11740008_s_at
11740009_a_at
11750964_s_at
16798765
210123_s_at
236385_at
29422
2MAW
33624
39566_at
5AFH
5AFJ
5AFK
5AFL
5AFM
5AFN
69847_at
7982341
7987012
80966_at
A_23_P163390
A_32_P35969
A_33_P3313519
A_33_P3719083
CAB033624
CCDS10027
CCDS53924
CHRNA7
CHRNA7-201
CHRNA7-202
CHRNA7-203
ENSG00000175344
ENSP00000303727
ENSP00000399087
ENSP00000407546
ENST00000306901
ENST00000437966
ENST00000454250
EntrezGene:101929970
EntrezGene:1139
g1458119_3p_a_at
GE80948
GO:0000187
GO:0001540
GO:0001666
GO:0001933
GO:0001934
GO:0001988
GO:0005216
GO:0005230
GO:0005262
GO:0005515
GO:0005886
GO:0005892
GO:0006810
GO:0006811
GO:0006816
GO:0006874
GO:0006897
GO:0007165
GO:0007271
GO:0007611
GO:0007613
GO:0007614
GO:0008284
GO:0008306
GO:0009409
GO:0009897
GO:0014061
GO:0015276
GO:0015464
GO:0015643
GO:0016020
GO:0016021
GO:0016324
GO:0017081
GO:0022848
GO:0030054
GO:0030317
GO:0030673
GO:0032094
GO:0032225
GO:0032691
GO:0032715
GO:0032720
GO:0033138
GO:0034220
GO:0035094
GO:0035095
GO:0042110
GO:0042113
GO:0042166
GO:0042391
GO:0042698
GO:0042803
GO:0044853
GO:0045202
GO:0045211
GO:0045471
GO:0045766
GO:0048149
GO:0048813
GO:0050727
GO:0050728
GO:0050804
GO:0050808
GO:0050890
GO:0050893
GO:0051247
GO:0060078
GO:0060079
GO:0060112
GO:0070374
GO:0070588
GO:0095500
GO:0097061
GO:0098794
GO:0098815
GO:1900273
GO:1901214
GO:1902004
GO:1902430
GO:1902991
GO:1904645
GO:1905144
GO:1905906
GO:1905920
GO:2000463
HGNC:1960
HPA029422
Hs.207457.0.A1_3p_at
ILMN_1676826
ILMN_1683373
ILMN_1788789
ILMN_1791501
ILMN_1845868
ILMN_3237574
LOC101929970
MIM:118511
MIM:612001
NM_000746
NM_001190455
NP_000737
NP_001177384
NR_046324
PF02931
PF02932
PH_hs_0027395
PH_hs_0040493
PR00252
PR00254
TC15002129.hg
TC15002755.hg
uc001zft.5
uc021sic.3
uc059hdo.1
UPI000003581A
UPI0000E23BA6
UPI0002467173
X70297_at
XM_011508492
XM_011521178
XM_016999550
XP_011506794
XP_011519480
XP_016855039
Participant Of
hasMember
acetylcholine receptor subunits [plasma membrane]
hasComponent
Acetylcholine receptor containing alpha7 subunit [plasma membrane]
Inferred To
Homologues of CHRNA7 [plasma membrane] (Bos taurus)
Homologues of CHRNA7 [plasma membrane] (Caenorhabditis elegans)
Homologues of CHRNA7 [plasma membrane] (Danio rerio)
Homologues of CHRNA7 [plasma membrane] (Drosophila melanogaster)
Homologues of CHRNA7 [plasma membrane] (Rattus norvegicus)
CHRNA7 [plasma membrane] (Bos taurus)
CHRNA7 [plasma membrane] (Caenorhabditis elegans)
CHRNA7 [plasma membrane] (Canis familiaris)
CHRNA7 [plasma membrane] (Danio rerio)
CHRNA7 [plasma membrane] (Drosophila melanogaster)
CHRNA7 [plasma membrane] (Gallus gallus)
CHRNA7 [plasma membrane] (Mus musculus)
CHRNA7 [plasma membrane] (Rattus norvegicus)
CHRNA7 [plasma membrane] (Sus scrofa)
CHRNA7 [plasma membrane] (Taeniopygia guttata)
CHRNA7 [plasma membrane] (Xenopus tropicalis)
Cross References
RefSeq
NP_000737.1
,
XP_016877373.1
,
NP_683709.1
,
XP_005254807.1
,
NP_001177384.1
ZINC - World Drugs
ACHA7_HUMAN
ZINC - FDA approved
ACHA7_HUMAN
ZINC - Substances
ACHA7_HUMAN
ZINC target
P36544
ZINC - Biogenic
ACHA7_HUMAN
PRO
P36544
PDB
5AFN
,
2MAW
,
5AFM
,
5AFL
,
5AFK
,
5AFJ
,
5AFH
ZINC - Metabolites
ACHA7_HUMAN
GeneCards
P36544
DOCK Blaster
5AFH
,
5AFN
,
5AFL
,
5AFM
,
5AFJ
,
5AFK
ZINC - Predictions - Purchasable
ACHA7_HUMAN
Orphanet
20105
HMDB Protein
HMDBP12048
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05067 APP
14
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.463
2
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