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CHRNB4 [plasma membrane]
Stable Identifier
R-HSA-507821
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Neuronal acetylcholine receptor subunit beta-4, ACHB4_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Exocytosis of tertiary granule membrane proteins (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Acetylcholine binding and downstream events (Homo sapiens)
Postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
O-acteylcholine bound to calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor containing alpha7 subunit [plasma membrane] (Homo sapiens)
acetylcholine receptor subunits [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor containing alpha7 subunit [plasma membrane] (Homo sapiens)
acetylcholine receptor subunits [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
O-acteylcholine bound to calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor containing alpha7 subunit [plasma membrane] (Homo sapiens)
acetylcholine receptor subunits [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Homo sapiens)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3(2)-beta4(3) [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3(2)-beta4(3) [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3(2)-beta4(3) [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Presynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly calcium permeable nicotinic acetylcholine receptors (Homo sapiens)
Activation of highly calcium permeable nicotinic acetylcholine receptors (Homo sapiens)
0-acteylcholine bound to calcium permeable nictonic acteylcholine receptor complex [plasma membrane] (Homo sapiens)
Highly calcium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4-apha5 [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha6 beta3 beta4 [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Homo sapiens)
0-acteylcholine bound to calcium permeable nictonic acteylcholine receptor complex [plasma membrane] (Homo sapiens)
Highly calcium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4-apha5 [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha6 beta3 beta4 [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Highly calcium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4-apha5 [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha6 beta3 beta4 [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Homo sapiens)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3(2)-beta4(3) [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3(2)-beta4(3) [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
O-Acetylcholine bound to Acetylcholine receptor [plasma membrane] (Homo sapiens)
Highly sodium permeable nicotinic acetylcholine receptors [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3(2)-beta4(3) [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
CHRNB4 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P30926 CHRNB4
Gene Names
CHRNB4
Chain
signal peptide:1-21, chain:22-498
Reference Genes
BioGPS Gene:1143 CHRNB4
COSMIC (genes):CHRNB4 CHRNB4
CTD Gene:1143 CHRNB4
dbSNP Gene:1143 CHRNB4
ENSEMBL:ENSG00000117971 CHRNB4
ENSEMBL_homo_sapiens_GENE:ENSG00000117971.12 CHRNB4
HGNC:1964 CHRNB4
KEGG Gene (Homo sapiens):1143 CHRNB4
Monarch:1143 CHRNB4
NCBI Gene:1143 CHRNB4
OMIM:118509 CHRNB4
UCSC:P30926 CHRNB4
Reference Transcript
RefSeq:NM_001256567.1 CHRNB4
RefSeq:NM_000750.3 CHRNB4
Other Identifiers
1143
11736940_at
11736941_at
207516_PM_at
207516_at
2360350
33568_at
3634683
3634684
3634685
3634686
3634687
3634690
3634692
3634697
3634698
3634699
7990729
A_23_P332789
GE59197
GO:0003012
GO:0003014
GO:0004888
GO:0005215
GO:0005216
GO:0005230
GO:0005515
GO:0005886
GO:0005892
GO:0006811
GO:0006939
GO:0006940
GO:0007154
GO:0007165
GO:0007271
GO:0007626
GO:0015276
GO:0015464
GO:0016020
GO:0019228
GO:0022848
GO:0023052
GO:0031410
GO:0034220
GO:0035094
GO:0035095
GO:0035579
GO:0042391
GO:0043005
GO:0043226
GO:0045202
GO:0045211
GO:0046928
GO:0050877
GO:0051971
GO:0055085
GO:0060078
GO:0060079
GO:0060084
GO:0060089
GO:0070821
GO:0098981
GO:1904315
HMNXSV003002760
PH_hs_0031235
U48861_at
g4502836_3p_at
Participates
as a member of
acetylcholine receptor subunits [plasma membrane] (Homo sapiens)
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
as a component of
Acetylcholine receptor alpha3(2)-beta4(3) [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha3-beta4-apha5 [plasma membrane] (Homo sapiens)
Acetylcholine receptor alpha6 beta3 beta4 [plasma membrane] (Homo sapiens)
Other forms of this molecule
CHRNB4 [specific granule membrane]
CHRNB4 [tertiary granule membrane]
Inferred To
acr-12 [plasma membrane]
(Caenorhabditis elegans)
unc-63 [plasma membrane]
(Caenorhabditis elegans)
acr-8 [plasma membrane]
(Caenorhabditis elegans)
lev-1 [plasma membrane]
(Caenorhabditis elegans)
nAChRalpha2 [plasma membrane]
(Drosophila melanogaster)
CHRNB4 [plasma membrane]
(Bos taurus)
CHRNB4 [plasma membrane]
(Canis familiaris)
CHRNB4 [plasma membrane]
(Gallus gallus)
nAChRalpha3 [plasma membrane]
(Drosophila melanogaster)
unc-29 [plasma membrane]
(Caenorhabditis elegans)
Homologues of CHRNB4 [plasma membrane]
(Caenorhabditis elegans)
Homologues of CHRNB4 [plasma membrane]
(Drosophila melanogaster)
Chrnb4 [plasma membrane]
(Mus musculus)
Chrnb4 [plasma membrane]
(Rattus norvegicus)
acr-3 [plasma membrane]
(Caenorhabditis elegans)
nAChRalpha4 [plasma membrane]
(Drosophila melanogaster)
acr-6 [plasma membrane]
(Caenorhabditis elegans)
nAChRbeta2 [plasma membrane]
(Drosophila melanogaster)
acr-2 [plasma membrane]
(Caenorhabditis elegans)
lev-8 [plasma membrane]
(Caenorhabditis elegans)
chrnb4 [plasma membrane]
(Xenopus tropicalis)
nAChRalpha1 [plasma membrane]
(Drosophila melanogaster)
nAChRbeta1 [plasma membrane]
(Drosophila melanogaster)
unc-38 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001243496.1
,
NP_000741.1
Guide to Pharmacology - Targets
474
OpenTargets
ENSG00000117971
GeneCards
P30926
HPA
ENSG00000117971-CHRNB4
Ensembl
ENST00000412074
,
ENSG00000117971
,
ENSP00000416386
,
ENST00000261751
,
ENSP00000261751
PRO
P30926
Pharos - Targets
P30926
HMDB Protein
HMDBP12046
PDB
6PV8
,
6PV7
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