GLUT1,2

Stable Identifier
R-HSA-500048
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
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Summation

Human pancreatic beta cells contain GLUT1 and GLUT2 transporters, with GLUT1 predominant. Rodent beta cells predominantly contain GLUT2, which may account for differences observed in the toxicity of streptozotocin.

Literature References
PubMed ID Title Journal Year
7593639 Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression

De Vos, A, Heimberg, H, Quartier, E, Huypens, P, Bouwens, L, Pipeleers, D, Schuit, F

J Clin Invest 1995
17380317 Low levels of glucose transporters and K+ATP channels in human pancreatic beta cells early in development

Richardson, CC, Hussain, K, Jones, PM, Persaud, S, Löbner, K, Boehm, A, Clark, A, Christie, MR

Diabetologia 2007
7589840 Pancreatic islet GLUT2 glucose transporter mRNA and protein expression in humans with and without NIDDM

Ferrer, J, Benito, C, Gomis, R

Diabetes 1995
Participants
members
Inferred To
GLUT1,2 [plasma membrane] (Arabidopsis thaliana)
GLUT1,2 [plasma membrane] (Bos taurus)
GLUT1,2 [plasma membrane] (Caenorhabditis elegans)
GLUT1,2 [plasma membrane] (Canis familiaris)
GLUT1,2 [plasma membrane] (Danio rerio)
GLUT1,2 [plasma membrane] (Dictyostelium discoideum)
GLUT1,2 [plasma membrane] (Drosophila melanogaster)
GLUT1,2 [plasma membrane] (Gallus gallus)
GLUT1,2 [plasma membrane] (Mus musculus)
GLUT1,2 [plasma membrane] (Oryza sativa)
GLUT1,2 [plasma membrane] (Rattus norvegicus)
GLUT1,2 [plasma membrane] (Taeniopygia guttata)
GLUT1,2 [plasma membrane] (Xenopus tropicalis)
GLUT2 / SLC2A2 tetramer [plasma membrane] (Sus scrofa)