p-S54,92,203-BRF1 binds 14-3-3

Stable Identifier
R-HSA-482788
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Phosphorylated BRF1 interacts with 14-3-3, becomes localized to the cytoskeleton, and no longer promotes RNA degradation. Phosphorylated BRF1 is, however, still able to bind RNA.

Literature References
PubMed ID Title Journal Year
18326031 The AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2

Maitra, S, Chou, CF, Luber, CA, Lee, KY, Mann, M, Chen, CY

RNA 2008
Participants
Participant Of
Orthologous Events
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Created