Exocytosis of platelet alpha granule contents

Stable Identifier
Reaction [transition]
Homo sapiens
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Alpha granules contain mainly polypeptides such as fibrinogen, von Willebrand factor, growth factors and protease inhibitors that supplement thrombin generation at the site of injury. In addtion to their role in hemostasis, platelets also contain angiogenesis stimulators and inhibitors (Italiano et al. 2008).

Literature References
PubMed ID Title Journal Year
23640497 High precision platelet releasate definition by quantitative reversed protein profiling--brief report

Roest, M, Heck, AJ, Scholten, A, Bleijerveld, OB, Wijten, P, Woo, LL, van Holten, T

Arterioscler. Thromb. Vasc. Biol. 2013
8467233 Platelet alpha-granules

Cramer, EM, Harrison, P

Blood Rev 1993
6457647 Characterization of the proteins of isolated human platelet alpha-granules. Evidence for a separate alpha-granule-pool of the glycoproteins IIb and IIIa.

Hagen, I, Gogstad, GO, Solum, NO, Korsmo, R

Biochim Biophys Acta 1981
Orthologous Events
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