POU5F1:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG gene [nucleoplasm]

Stable Identifier
Homo sapiens
KLF4, PBX1, OCT4 (POU5F1), SOX2, and NANOG bind the promoter of the NANOG gene.
Literature References
PubMed ID Title Journal Year
18212089 High-throughput biochemical analysis of in vivo location data reveals novel distinct classes of POU5F1(Oct4)/DNA complexes

Gemberling, M, Tantin, D, Callister, C, Fairbrother, WG

Genome Res 2008
15743839 Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression

Tada, M, Nakatsuji, N, Kubota, H, Tada, T, Suemori, H, Hatano, SY, Kuroda, T, Kimura, H

Mol Cell Biol 2005
16153702 Core transcriptional regulatory circuitry in human embryonic stem cells

Gifford, DK, Jaenisch, R, Lee, TI, Young, RA, Kumar, RM, Guenther, MG, Levine, SS, Boyer, LA, Jenner, RG, Cole, MF, Zucker, JP, Murray, HL, Johnstone, SE, Melton, DA

Cell 2005
15860457 Transcriptional regulation of nanog by OCT4 and SOX2

Rodda, DJ, Robson, P, Lim, LH, Wang, B, Loh, YH, Ng, HH, Chew, JL

J Biol Chem 2005
19522013 KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells

Sim, HS, Chan, YS, Tan, KS, Zhang, J, Oh, SK, Chia, NY, Ng, HH, Chan, KK, Choo, AB

Stem Cells 2009
23178592 OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells

Robertson, M, Osorno, R, Gagliardi, A, Festuccia, N, Karwacki-Neisius, V, Mullin, NP, Chambers, I, Navarro, P, Zhang, W, Colby, D, Kelly, D

EMBO J. 2012
21630377 Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors

Dunn, NR, Lim, B, Cho, CH, Vallier, L, Pedersen, R, Hannan, N, Teo, A, Vardy, L, Brown, S, Trotter, M, Pauklin, S

Stem Cells 2011
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