HSF1:HSP90:PTGES3 [cytosol]

Stable Identifier
R-HSA-4793919
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
9727490 Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

Zou, J, Guo, Y, Guettouche, T, Smith, DF, Voellmy, R

Cell 1998
16403413 The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins

McLaughlin, SH, Sobott, F, Yao, ZP, Zhang, W, Nielsen, PR, Grossmann, JG, Laue, ED, Robinson, CV, Jackson, SE

J. Mol. Biol. 2006
11583998 Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex

Guo, Y, Guettouche, T, Fenna, M, Boellmann, F, Pratt, WB, Toft, DO, Smith, DF, Voellmy, R

J. Biol. Chem. 2001
21183720 N-terminal domain of human Hsp90 triggers binding to the cochaperone p23

Karagöz, GE, Duarte, AM, Ippel, H, Uetrecht, C, Sinnige, T, van Rosmalen, M, Hausmann, J, Heck, AJ, Boelens, R, Rüdiger, SG

Proc. Natl. Acad. Sci. U.S.A. 2011
Participants
components
Participant Of
input
Inferred To
HSF1:HSP90:PTGES3 [cytosol] (Caenorhabditis elegans)
HSF1:HSP90:PTGES3 [cytosol] (Canis familiaris)
HSF1:HSP90:PTGES3 [cytosol] (Danio rerio)
HSF1:HSP90:PTGES3 [cytosol] (Dictyostelium discoideum)
HSF1:HSP90:PTGES3 [cytosol] (Drosophila melanogaster)
HSF1:HSP90:PTGES3 [cytosol] (Gallus gallus)
HSF1:HSP90:PTGES3 [cytosol] (Mus musculus)
HSF1:HSP90:PTGES3 [cytosol] (Rattus norvegicus)
HSF1:HSP90:PTGES3 [cytosol] (Saccharomyces cerevisiae)
HSF1:HSP90:PTGES3 [cytosol] (Schizosaccharomyces pombe)
HSF1:HSP90:PTGES3 [cytosol] (Sus scrofa)
HSF1:HSP90:PTGES3 [cytosol] (Xenopus tropicalis)
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