Reactome | SUMO3-RELA:SUMO3-RELA [nucleoplasm]

SUMO3-RELA:SUMO3-RELA [nucleoplasm]

Stable Identifier

R-HSA-4755537

Type

Complex

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

SUMO3-RELA Dimer

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - SUMOylation (Homo sapiens)
    - SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
      - SUMOylation of immune response proteins (Homo sapiens)
        
        PIAS3 SUMOylates RELA with SUMO3 (Homo sapiens)
        
        SUMO3-RELA:SUMO3-RELA:DNA [nucleoplasm] (Homo sapiens)
        
        SUMO3-RELA:SUMO3-RELA [nucleoplasm] (Homo sapiens)

Literature References

PubMed ID	Title	Journal	Year
25218447	Uncovering global SUMOylation signaling networks in a site-specific manner Hendriks, IA, D'Souza, RC, Yang, B, Verlaan-de Vries, M, Mann, M, Vertegaal, AC	Nat. Struct. Mol. Biol.	2014
22649547	NF-?B repression by PIAS3 mediated RelA SUMOylation Liu, Y, Bridges, R, Wortham, A, Kulesz-Martin, M	PLoS ONE	2012

Participants

components

2 x SUMO3-K37,K122,K123-RELA [nucleoplasm] (Homo sapiens)

Participant Of

hasComponent

SUMO3-RELA:SUMO3-RELA:DNA [nucleoplasm]

Inferred To

SUMO3-RELA:SUMO3-RELA [nucleoplasm] (Bos taurus)

SUMO3-RELA:SUMO3-RELA [nucleoplasm] (Canis familiaris)

SUMO3-RELA:SUMO3-RELA [nucleoplasm] (Danio rerio)

SUMO3-RELA:SUMO3-RELA [nucleoplasm] (Drosophila melanogaster)

SUMO3-RELA:SUMO3-RELA [nucleoplasm] (Mus musculus)

SUMO3-RELA:SUMO3-RELA [nucleoplasm] (Rattus norvegicus)

SUMO3-RELA:SUMO3-RELA [nucleoplasm] (Sus scrofa)

SUMO3-RELA:SUMO3-RELA [nucleoplasm] (Xenopus tropicalis)

© 2020 Reactome