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3SUMO1:THRB [nucleoplasm]
Stable Identifier
R-HSA-4719435
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of intracellular receptors (Homo sapiens)
PIAS1 SUMOylates THRB with SUMO1. (Homo sapiens)
3SUMO1:THRB [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
22930759
Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation
Liu, YY
,
Kogai, T
,
Schultz, JJ
,
Mody, K
,
Brent, GA
J. Biol. Chem.
2012
Participants
components
K146-THRB-G97-SUMO1 [nucleoplasm] (Homo sapiens)
K443-THRB-G97-SUMO1 [nucleoplasm] (Homo sapiens)
K50-THRB-G97-SUMO1 [nucleoplasm] (Homo sapiens)
SUMO1-K50,K146,K443-THRB [nucleoplasm] (Homo sapiens)
Participant Of
output
PIAS1 SUMOylates THRB with SUMO1.
Inferred To
3SUMO1:THRB [nucleoplasm] (Bos taurus)
3SUMO1:THRB [nucleoplasm] (Caenorhabditis elegans)
3SUMO1:THRB [nucleoplasm] (Canis familiaris)
3SUMO1:THRB [nucleoplasm] (Danio rerio)
3SUMO1:THRB [nucleoplasm] (Gallus gallus)
3SUMO1:THRB [nucleoplasm] (Mus musculus)
3SUMO1:THRB [nucleoplasm] (Rattus norvegicus)
3SUMO1:THRB [nucleoplasm] (Sus scrofa)
3SUMO1:THRB [nucleoplasm] (Xenopus tropicalis)
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