Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
monoSUMO1-K250-NR2C1 [nucleoplasm]
Stable Identifier
R-HSA-4717448
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Nuclear receptor subfamily 2 group C member 1, NR2C1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of intracellular receptors (Homo sapiens)
PIAS1 SUMOylates NR2C1 (TR2) (Homo sapiens)
monoSUMO1-K250-NR2C1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P13056 NR2C1
Gene Names
NR2C1, TR2
Chain
chain:1-603
Reference Genes
BioGPS Gene:7181 NR2C1
COSMIC (genes):NR2C1 NR2C1
CTD Gene:7181 NR2C1
dbSNP Gene:7181 NR2C1
ENSEMBL:ENSG00000120798 NR2C1
HGNC:7971 NR2C1
KEGG Gene (Homo sapiens):7181 NR2C1
Monarch:7181 NR2C1
NCBI Gene:7181 NR2C1
OMIM:601529 NR2C1
UCSC:P13056 NR2C1
Reference Transcript
RefSeq:NM_001127362.1 NR2C1
RefSeq:NM_001032287.2 NR2C1
RefSeq:NM_003297.3 NR2C1
Other Identifiers
0005550292
11721273_at
11721274_a_at
11735877_a_at
11753015_a_at
11763442_a_at
1406_at
1407_g_at
16768646
204791_at
210530_s_at
210531_at
229956_at
3466316
3466317
3466319
3466320
3466321
3466322
3466323
3466325
3466328
3466329
3466330
3466331
3466332
3466333
3466335
3466338
3466341
3466343
3466347
3466348
3466351
3466352
3466354
3466355
3466358
3466360
582_g_at
603_at
7181
74019_at
7965523
85933_r_at
A_23_P204828
A_24_P78540
A_33_P3302220
GE57912
GE865865
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001227
GO:0003674
GO:0003677
GO:0003700
GO:0003707
GO:0004879
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0006355
GO:0006357
GO:0006367
GO:0007165
GO:0008150
GO:0008270
GO:0009058
GO:0016605
GO:0019899
GO:0030154
GO:0030522
GO:0034641
GO:0038023
GO:0042803
GO:0042826
GO:0043167
GO:0043226
GO:0043401
GO:0043565
GO:0045892
GO:0046872
GO:0048386
GO:0048856
GO:1990837
HMNXSV003005850
HMNXSV003055936
Hs.126679.0.A1_3p_at
ILMN_1728983
ILMN_1734867
ILMN_1774382
ILMN_2326675
M21985_at
M29960_at
PH_hs_0006000
TC12001828.hg
g338485_3p_a_at
g4507672_3p_at
Participates
as an output of
PIAS1 SUMOylates NR2C1 (TR2) (Homo sapiens)
Other forms of this molecule
NR2C1 [nucleoplasm]
Modified Residues
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 250
Coordinate
250
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
RefSeq
NP_003288.2
,
NP_001027458.1
,
NP_001120834.1
Guide to Pharmacology - Targets
613
OpenTargets
ENSG00000120798
GeneCards
P13056
HPA
ENSG00000120798-NR2C1
Ensembl
ENST00000393101
,
ENSP00000333275
,
ENSP00000328843
,
ENST00000333003
,
ENST00000330677
,
ENSG00000120798
,
ENSP00000376813
PRO
P13056
Pharos - Targets
P13056
© 2022
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text