Ubiquitinated DVL1 is degraded by the proteasome

Stable Identifier
R-HSA-4641260
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

After ubiquitination by HECW1, DVL1 is degraded by the proteasome.

Literature References
PubMed ID Title Journal Year
14684739 NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1

Miyazaki, K, Fujita, T, Ozaki, T, Kato, C, Kurose, Y, Sakamoto, M, Kato, S, Goto, T, Itoyama, Y, Aoki, M, Nakagawara, A

J. Biol. Chem. 2004
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
endopeptidase activity of 26S proteasome [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created