Ubiquitinated DVL1 is degraded by the proteasome

Stable Identifier
R-HSA-4641260
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
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After ubiquitination by HECW1, DVL1 is degraded by the proteasome.

Literature References
PubMed ID Title Journal Year
14684739 NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1

Miyazaki, K, Aoki, M, Itoyama, Y, Ozaki, T, Goto, T, Kurose, Y, Fujita, T, Kato, S, Kato, C, Nakagawara, A, Sakamoto, M

J. Biol. Chem. 2004
Participants
Participates
Catalyst Activity

endopeptidase activity of 26S proteasome [cytosol]

Orthologous Events
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