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RSPO2 [extracellular region]
Stable Identifier
R-HSA-4641196
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Regulation of FZD by ubiquitination (Homo sapiens)
RSPO:LGR binds ZNRF3 (Homo sapiens)
RSPO:LGR [plasma membrane] (Homo sapiens)
RSPO [extracellular region] (Homo sapiens)
RSPO2 [extracellular region] (Homo sapiens)
RSPO:LGR:ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
RSPO:LGR [plasma membrane] (Homo sapiens)
RSPO [extracellular region] (Homo sapiens)
RSPO2 [extracellular region] (Homo sapiens)
RSPOs bind LGRs (Homo sapiens)
RSPO [extracellular region] (Homo sapiens)
RSPO2 [extracellular region] (Homo sapiens)
RSPO:LGR [plasma membrane] (Homo sapiens)
RSPO [extracellular region] (Homo sapiens)
RSPO2 [extracellular region] (Homo sapiens)
ZNRF3 autoubiquitinates to promote its internalization (Homo sapiens)
RSPO:LGR:ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
RSPO:LGR [plasma membrane] (Homo sapiens)
RSPO [extracellular region] (Homo sapiens)
RSPO2 [extracellular region] (Homo sapiens)
RSPO:LGR:ub-ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
RSPO [extracellular region] (Homo sapiens)
RSPO2 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6UXX9 RSPO2
Gene Names
RSPO2, UNQ9384/PRO34209
Chain
signal peptide:1-21, chain:22-243
Reference Genes
BioGPS Gene:340419 RSPO2
COSMIC (genes):RSPO2 RSPO2
CTD Gene:340419 RSPO2
dbSNP Gene:340419 RSPO2
ENSEMBL:ENSG00000147655 RSPO2
HGNC:28583 RSPO2
KEGG:hsa:340419 RSPO2
Monarch:340419 RSPO2
NCBI Gene:340419 RSPO2
OMIM:610575 RSPO2
UCSC:Q6UXX9 RSPO2
Reference Transcript
RefSeq:NM_001317942.2 RSPO2
RefSeq:NM_178565.4 RSPO2
RefSeq:NM_001282863.2 RSPO2
Participates
as a member of
RSPO [extracellular region] (Homo sapiens)
Inferred To
RSPO2 [extracellular region]
(Bos taurus)
RSPO2 [extracellular region]
(Canis familiaris)
RSPO2 [extracellular region]
(Gallus gallus)
RSPO2 [extracellular region]
(Sus scrofa)
rspo2 [extracellular region]
(Danio rerio)
rspo2 [extracellular region]
(Xenopus tropicalis)
Rspo2 [extracellular region]
(Mus musculus)
Rspo2 [extracellular region]
(Rattus norvegicus)
Cross References
RefSeq
NP_001304871.1
,
NP_001269792.1
,
NP_848660.3
ENSEMBL
ENST00000517781
,
ENSP00000276659
,
ENSP00000428940
,
ENSG00000147655
,
ENST00000276659
,
ENST00000517939
,
ENSP00000427937
OpenTargets
ENSG00000147655
GeneCards
RSPO2
HPA
ENSG00000147655-RSPO2
PRO
Q6UXX9
Pharos - Targets
Q6UXX9
GlyGen
Q6UXX9
Orphanet
RSPO2
PDB
8Y69
,
8XFS
,
8XFT
,
8XUM
,
8XFP
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