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ZNRF3 [plasma membrane]
Stable Identifier
R-HSA-4641179
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
RNF203, KIAA1133
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Regulation of FZD by ubiquitination (Homo sapiens)
RSPO:LGR binds ZNRF3 (Homo sapiens)
RSPO:LGR:ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
ZNRF3 [plasma membrane] (Homo sapiens)
ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
ZNRF3 [plasma membrane] (Homo sapiens)
ZNRF3 autoubiquitinates to promote its internalization (Homo sapiens)
RSPO:LGR:ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
ZNRF3 [plasma membrane] (Homo sapiens)
ZNRF3 ubiquitinates FZD to promote its downregulation (Homo sapiens)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane] (Homo sapiens)
ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
ZNRF3 [plasma membrane] (Homo sapiens)
N4GlycoAsn-PalmS-WNT3A:ub-FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane] (Homo sapiens)
ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
ZNRF3 [plasma membrane] (Homo sapiens)
ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Homo sapiens)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane] (Homo sapiens)
ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
ZNRF3 [plasma membrane] (Homo sapiens)
ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
ZNRF3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9ULT6 ZNRF3
Gene Names
ZNRF3, KIAA1133, RNF203
Chain
signal peptide:1-55, chain:56-936
Reference Genes
BioGPS Gene:84133 ZNRF3
COSMIC (genes):ZNRF3 ZNRF3
CTD Gene:84133 ZNRF3
dbSNP Gene:84133 ZNRF3
ENSEMBL:ENSG00000183579 ZNRF3
HGNC:18126 ZNRF3
KEGG:hsa:84133 ZNRF3
Monarch:84133 ZNRF3
NCBI Gene:84133 ZNRF3
OMIM:612062 ZNRF3
UCSC:Q9ULT6 ZNRF3
Reference Transcript
RefSeq:NM_032173.3 ZNRF3
RefSeq:NM_001206998.1 ZNRF3
Other Identifiers
11725537_at
16928699
226360_PM_at
226360_at
3941691
3941692
3941701
3941710
3941735
3941736
3941737
3941738
3941740
3941741
3941742
3941743
3941744
3941748
3941749
3941750
3941751
3941752
60034_at
77685_at
8072160
84133
A_14_P134974
A_23_P427502
A_24_P162373
GE488298
GE53785
GO:0003824
GO:0004842
GO:0005109
GO:0005515
GO:0005886
GO:0006511
GO:0016055
GO:0016567
GO:0016740
GO:0030178
GO:0038018
GO:0046872
GO:0048856
GO:0060173
GO:0060828
GO:0061630
GO:0072089
GO:0090090
GO:0140096
GO:2000051
GO:2000095
HMNXSV003034804
Hs.318584.0.S1_3p_at
ILMN_1788738
PH_hs_0035374
TC22000189.hg
Participates
as a member of
ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
Other forms of this molecule
ub-ZNRF3 [plasma membrane]
Inferred To
znrf3 [plasma membrane]
(Danio rerio)
znrf3 [plasma membrane]
(Xenopus tropicalis)
plr-1 [plasma membrane]
(Caenorhabditis elegans)
ZNRF3 [plasma membrane]
(Bos taurus)
ZNRF3 [plasma membrane]
(Canis familiaris)
ZNRF3 [plasma membrane]
(Gallus gallus)
ZNRF3 [plasma membrane]
(Sus scrofa)
Znrf3 [plasma membrane]
(Mus musculus)
Znrf3 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_115549.2
,
NP_001193927.1
ENSEMBL
ENSP00000384456
,
ENST00000402174
,
ENST00000406323
,
ENST00000544604
,
ENSP00000384553
,
ENSP00000443824
OpenTargets
ENSG00000183579
HPA
ENSG00000183579-ZNRF3
PRO
Q9ULT6
Pharos - Targets
Q9ULT6
PDB
8G4Y
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