Reactome | DACT1 [cytosol]

DACT1 [cytosol]

Stable Identifier

R-HSA-4641144

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

DAPPER1, HNG3, DPR1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NYF0 DACT1

Gene Names

DACT1, DPR1, HNG3

Chain

chain:1-836

Reference Genes

BioGPS Gene:51339 DACT1

COSMIC (genes):DACT1 DACT1

CTD Gene:51339 DACT1

dbSNP Gene:51339 DACT1

ENSEMBL:ENSG00000165617.15 DACT1

HGNC:17748 DACT1

KEGG Gene (Homo sapiens):51339 DACT1

Monarch:51339 DACT1

NCBI Gene:51339 DACT1

OMIM:607861 DACT1

UCSC:Q9NYF0 DACT1

Reference Transcript

Other Identifiers

11735385_s_at

11735386_a_at

16784760

219179_PM_at

219179_at

3538093

3538094

3538095

3538096

3538098

3538099

3538103

3538104

3538105

3538106

3538107

3538108

3538109

51339

52970_at

7974689

A_14_P125198

A_23_P65518

A_24_P284093

GE498904

GE58736

GO:0000122

GO:0000278

GO:0005080

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006351

GO:0006355

GO:0007399

GO:0008013

GO:0009968

GO:0016055

GO:0021915

GO:0023052

GO:0030163

GO:0030177

GO:0030178

GO:0030877

GO:0031647

GO:0032091

GO:0032092

GO:0042826

GO:0043226

GO:0045202

GO:0045732

GO:0046329

GO:0048619

GO:0048856

GO:0051018

GO:0060828

GO:0061629

GO:0065003

GO:0070097

GO:0090090

GO:0090263

GO:1904864

GO:2000095

GO:2000134

HMNXSV003004626

ILMN_1801068

ILMN_2250344

ILMN_2328094

PH_hs_0003421

TC14000353.hg

g8393715_3p_at

p33675

Participates

as a component of

DVL2:DACT1 [cytosol] (Homo sapiens)

as an input of

DACT1 binds DVL2 (Homo sapiens)

Inferred To

Dact1 [cytosol] (Mus musculus)

Dact1 [cytosol] (Rattus norvegicus)

DACT1 [cytosol] (Bos taurus)

DACT1 [cytosol] (Canis familiaris)

DACT1 [cytosol] (Gallus gallus)

DACT1 [cytosol] (Sus scrofa)

dact1 [cytosol] (Danio rerio)

dact1 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001072988.1, NP_057735.2, XP_006720230.1

OpenTargets

ENSG00000165617

GeneCards

Q9NYF0

HPA

ENSG00000165617-DACT1

Ensembl

ENSP00000378582, ENST00000335867, ENSP00000337439, ENST00000395153, ENSG00000165617

PRO

Q9NYF0

Pharos - Targets

Q9NYF0

Orphanet

21552

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14641 DVL2	5	pp-DVL2 [cytosol] (R-HSA-3772398) p-DVL2 [cytosol] (R-HSA-201706) p-DVL2 [clathrin-coated endocytic vesicle] (R-HSA-5138444) DVL2 [cytosol] (R-HSA-201694) ub-DVL2 [cytosol] (R-HSA-4652689)	0.646	6
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.581	4
UniProt:P35222 CTNNB1	20	CTNNB1 S45A [cytosol] (R-HSA-9663982) CTNNB1 S45F [cytosol] (R-HSA-4791268) CTNNB1 S45C [cytosol] (R-HSA-9663983) CTNNB1 S45Y [cytosol] (R-HSA-9663975) CTNNB1 S45N [cytosol] (R-HSA-9663984) CTNNB1 S45P [cytosol] (R-HSA-4791272) pT41,S45-CTNNB1 S37P [cytosol] (R-HSA-9663981) pT41,S45-CTNNB1 S37F [cytosol] (R-HSA-4839621) pT41,S45-CTNNB1 S37A [cytosol] (R-HSA-4839619) pT41,S45-CTNNB1 S37Y [cytosol] (R-HSA-9663978) pT41,S45-CTNNB1 S37C [cytosol] (R-HSA-4839617) pS37,T41,S45-CTNNB1 S33A [cytosol] (R-HSA-9663976) pS37,T41,S45-CTNNB1 S33T [cytosol] (R-HSA-9663977) pS37,T41,S45-CTNNB1 S33C [cytosol] (R-HSA-4839630) pS37,T41,S45-CTNNB1 S33F [cytosol] (R-HSA-4839628) pS37,T41,S45-CTNNB1 S33P [cytosol] (R-HSA-4839626) pS37,T41,S45-CTNNB1 S33Y [cytosol] (R-HSA-4839625) pS45-CTNNB1 T41N [cytosol] (R-HSA-9663980) pS45-CTNNB1 T41A [cytosol] (R-HSA-4836868) pS45-CTNNB1 T41I [cytosol] (R-HSA-4839612)	0.537	3
UniProt:P49841 GSK3B	4	GSK3B del304-316 [cytosol] (R-HSA-5339682) GSK3B [nucleoplasm] (R-HSA-2022823) p-S9-GSK3B [cytosol] (R-HSA-3149577) GSK3B [cytosol] (R-HSA-2997551)	0.537	3

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