SMURF2 has been shown to ubiquitinate AXIN at lysine 505 both in vitro and in vivo in a manner that depends on the interaction between the two proteins (Kim and Jho, 2012).
Jho, EH, Kim, S
ubiquitin protein ligase activity of AXIN:SMURF2 [cytosol]
© 2023 Reactome