monoSUMO1-K444,K476-HDAC1 [nucleoplasm]

Stable Identifier
R-HSA-4616030
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Histone deacetylase 1, HDAC1_HUMAN
monoSUMO1-K444,K476-HDAC1 [nucleoplasm] icon
Locations in the PathwayBrowser for interactor UniProt:P46531 NOTCH1
External Reference Information
External Reference
Gene Names
HDAC1, RPD3L1
Chain
chain:1-482
Reference Transcript
Other Identifiers
11747406_a_at
11755718_s_at
16662077
201209_PM_at
201209_at
2328869
2328870
2328872
2328873
2328878
2328879
2328882
2328885
2328889
2328890
2328891
2328892
2328894
2328896
2328898
2328900
2381219
2927725
3065
38771_at
476_s_at
7899774
A_14_P114672
A_23_P114656
D50405_at
GE57241
GO:0000118
GO:0000122
GO:0000228
GO:0000785
GO:0000792
GO:0000976
GO:0000978
GO:0000979
GO:0001046
GO:0001222
GO:0002039
GO:0003677
GO:0003682
GO:0003714
GO:0003824
GO:0004407
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0006325
GO:0006338
GO:0006346
GO:0006351
GO:0006355
GO:0006357
GO:0006476
GO:0007492
GO:0007623
GO:0008284
GO:0009913
GO:0010628
GO:0010629
GO:0012501
GO:0016575
GO:0016581
GO:0016787
GO:0017053
GO:0019899
GO:0021766
GO:0023052
GO:0030154
GO:0030182
GO:0030336
GO:0030512
GO:0031492
GO:0032922
GO:0032991
GO:0033558
GO:0035851
GO:0036120
GO:0036211
GO:0042475
GO:0042659
GO:0042733
GO:0042826
GO:0043025
GO:0043066
GO:0043124
GO:0043226
GO:0043922
GO:0045892
GO:0045893
GO:0045944
GO:0046872
GO:0048511
GO:0048661
GO:0048709
GO:0048714
GO:0048856
GO:0048870
GO:0051059
GO:0052548
GO:0060766
GO:0060789
GO:0061029
GO:0061198
GO:0061629
GO:0070822
GO:0070888
GO:0090090
GO:0140096
GO:0140110
GO:0140297
GO:0160008
GO:0160009
GO:1900221
GO:1902455
GO:1902459
GO:1990841
GO:2000273
GO:2000736
GO:2001243
HMNXSV003006637
ILMN_1727458
PH_hs_0004954
TC01000427.hg
U50079_s_at
g13128859_3p_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 444
Coordinate
444
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 476
Coordinate
476
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
ZINC - Investigational
GeneCards
Pharos - Targets
ZINC - Predictions - Purchasable
Interactors (173)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P06400 RB1  20 0.955 18
 UniProt:O94776 MTA2  1 0.951 19
 UniProt:Q92769 HDAC2  2 0.946 21
 UniProt:Q9UKL0 RCOR1  1 0.945 15
 UniProt:Q13330 MTA1  2 0.929 16
 UniProt:Q8N108 MIER1      0.926 12
 UniProt:Q14839 CHD4  1 0.924 15
 UniProt:Q96ST3 SIN3A  2 0.918 13
 UniProt:Q09028 RBBP4  1 0.916 14
 UniProt:Q16576 RBBP7  1 0.909 12
 UniProt:O95983 MBD3  1 0.899 10
 UniProt:Q9UBB5 MBD2  1 0.894 10
 UniProt:Q8WXI9 GATAD2B  1 0.877 10
 UniProt:O60341 KDM1A  1 0.855 12
 UniProt:Q92618 ZN516      0.84 12
 UniProt:Q86YP4 GATAD2A  1 0.837 8
 UniProt:Q5PSV4 BRM1L      0.837 8
 UniProt:Q6PJG2 MDEAS      0.837 9
 UniProt:O75446 SAP30  1 0.837 9
 UniProt:Q9H7L9 SUDS3  2 0.837 8
 UniProt:Q9NP66 HM20A      0.837 9
 UniProt:Q9BTC8 MTA3  1 0.837 9
 UniProt:Q9H147 TDIF1      0.837 10
 UniProt:Q14865 ARID5B  1 0.835 9
 UniProt:Q9NP50 SHCAF      0.835 10
 UniProt:Q9HCU9 BRMS1  1 0.832 8
 UniProt:Q12873 CHD3  2 0.805 9
 UniProt:Q96KQ7 EHMT2  1 0.794 9
 UniProt:O75182 SIN3B  1 0.788 7
 UniProt:Q14687 GSE1      0.788 7
 UniProt:Q9P0W2 HMG20B  1 0.788 7
 UniProt:P78371 CCT2  3 0.788 8
 UniProt:P50991 CCT4  1 0.788 7
 UniProt:Q7Z589 EMSY      0.788 7
 UniProt:Q9UBW7 ZMYM2  6 0.788 6
 UniProt:O14519 CDKA1      0.788 8
 UniProt:O75362 ZNF217  1 0.788 7
 UniProt:P17987 TCP1  1 0.788 7
 UniProt:Q96N64 PWP2A      0.787 8
 UniProt:Q6PH81 CP087      0.773 8
 UniProt:P68400 CSNK2A1  2 0.759 4
 UniProt:Q99832 CCT7  1 0.725 6
 UniProt:Q92766 RREB1      0.725 6
 UniProt:P61964 WDR5  1 0.725 4
 UniProt:Q9HAJ7 SAP30L  1 0.725 6
 UniProt:P48643 CCT5  1 0.725 5
 UniProt:O15417 TNC18      0.725 5
 UniProt:Q9H9B1 EHMT1  1 0.725 4
 UniProt:Q96QT6 PHF12      0.725 7
 UniProt:Q9P2R6 RERE      0.725 6
 UniProt:Q9H0E3 SAP130  1 0.725 6
 UniProt:Q14202 ZMYM3      0.725 6
 UniProt:Q9P2K3 RCOR3      0.725 6
 UniProt:Q13363 CTBP1  3 0.725 8
 UniProt:P49368 CCT3  1 0.725 7
 UniProt:Q8WUU5 GATD1      0.725 5
 UniProt:Q96PN7 TREF1      0.725 6
 UniProt:Q8N680 ZBTB2      0.725 5
 UniProt:Q9H160 ING2  2 0.725 6
 UniProt:P04637 TP53  20 0.713 7
 UniProt:Q05516 ZBTB16  1 0.702 6
 UniProt:Q9C0K0 BC11B      0.695 5
 UniProt:P01106 MYC  2 0.69 4
 UniProt:P62805 H4C1  17 0.688 3
 UniProt:Q04206 RELA  7 0.656 6
 UniProt:P19838 NFKB1  8 0.646 5
 UniProt:P85037 FOXK1  1 0.643 3
 UniProt:Q8IZ40 RCOR2      0.643 5
 UniProt:O15014 ZN609      0.643 3
 UniProt:Q14186 TFDP1  1 0.643 4
 UniProt:Q96BD5 PHF21A  1 0.643 5
 UniProt:O60315 ZEB2  1 0.643 10
 UniProt:Q99471 PFDN5  1 0.643 4
 UniProt:O95785 WIZ      0.643 3
 UniProt:Q8IWI9 MGA  1 0.643 5
 UniProt:P50990 CCT8  5 0.643 4
 UniProt:Q8N344 MIER2      0.643 5
 UniProt:Q9H165 BCL11A  2 0.643 4
 UniProt:P0C0S8 H2AC11  11 0.643 3
 UniProt:Q4LE39 ARID4B  1 0.643 5
 UniProt:Q9ULU4 ZMYD8      0.643 3
 UniProt:Q9P281 BAHC1      0.643 3
 UniProt:P61758 VBP1  1 0.643 3
 UniProt:Q96KM6 ZNF512B  1 0.643 3
 UniProt:P29374 ARID4A  1 0.643 5
 UniProt:Q7Z3K6 MIER3      0.643 5
 UniProt:O00629 KPNA4  2 0.643 3
 UniProt:Q8N1G0 ZN687      0.643 3
 UniProt:Q9BYE7 PCGF6  1 0.643 5
 UniProt:Q96K83 ZNF521  1 0.643 3
 UniProt:P52294 KPNA1  2 0.643 3
 UniProt:O75461 E2F6  2 0.643 4
 UniProt:O95863 SNAI1  1 0.642 3
 UniProt:Q2TB10 ZN800      0.615 3
 UniProt:P03372 ESR1  10 0.597 4
 UniProt:P26358 DNMT1  2 0.597 7
 UniProt:Q9Y618 NCOR2  2 0.589 2
 UniProt:Q01094 E2F1  2 0.589 2
 UniProt:P17844 DDX5  4 0.576 4
 UniProt:Q9NQX1 PRDM5      0.576 3
 UniProt:O60341-1 KDM1A      0.564 2
 UniProt:O95365 ZBT7A      0.564 2
 UniProt:P08047 SP1  1 0.564 2
 UniProt:P17542 TAL1  1 0.558 5
 UniProt:Q9UJW3 DNMT3L  1 0.544 3
 UniProt:Q99497 PARK7  7 0.537 4
 UniProt:P22670 RFX1      0.534 2
 UniProt:Q8N5A5 ZGPAT      0.532 3
 UniProt:Q17R98 ZN827      0.527 2
 UniProt:Q9P2K3-3 RCOR3      0.527 2
 UniProt:Q8IV32 CCD71      0.527 3
 UniProt:Q969G3 SMARCE1  1 0.527 2
 UniProt:Q6NUJ5 PWP2B      0.527 2
 UniProt:Q92526 CCT6B  1 0.527 3
 UniProt:Q14839-2 CHD4      0.527 2
 UniProt:P56545 CTBP2  1 0.527 2
 UniProt:Q4LE39-2 ARID4B      0.527 2
 UniProt:Q9UKL3 CASP8AP2  2 0.527 3
 UniProt:Q9UHF7 TRPS1      0.527 2
 UniProt:Q9R190 Mta2  1 0.527 2
 UniProt:Q9UHV9 PFDN2  1 0.527 2
 UniProt:P40227 CCT6A  1 0.527 3
 UniProt:O60925 PFDN1  1 0.527 2
 UniProt:Q9UK53 ING1      0.527 4
 UniProt:P29375-2 KDM5A      0.527 2
 UniProt:Q9Y232-2 CDYL      0.527 2
 UniProt:Q96BD5-2 PHF21A      0.527 2
 UniProt:Q9H2P0 ADNP      0.527 2
 UniProt:Q8WY36 BBX      0.527 2
 UniProt:Q9ULD9 ZN608      0.527 2
 UniProt:O75530 EED  1 0.527 3
 UniProt:IL2 ENSG00000109471      0.527 3
 UniProt:O75182-2 SIN3B      0.527 2
 UniProt:Q09028-2 RBBP4      0.527 2
 UniProt:Q5T5X7 BEND3      0.527 2
 UniProt:Q92610 ZN592      0.527 2
 UniProt:Q8WWY6 MB3L1      0.527 3
 UniProt:Q96EK2 PF21B      0.527 3
 UniProt:Q9P2Y4 ZN219      0.527 5
 UniProt:O15212 PFDN6  1 0.527 2
 UniProt:Q8TDI0 CHD5      0.527 4
 UniProt:Q8TBE0 BAHD1      0.527 3
 UniProt:Q96A08 H2BC1  9 0.527 4
 UniProt:Q96KQ7-2 EHMT2      0.527 2
 UniProt:Q9UHJ3 SMBT1      0.527 2
 UniProt:P29375 KDM5A  1 0.527 3
 UniProt:O60684 KPNA6  2 0.527 2
 UniProt:Q9Y232 CDYL      0.527 4
 UniProt:Q969R5 L3MBTL2  2 0.527 4
 UniProt:Q9NSC2 SALL1  1 0.527 2
 UniProt:Q8N4J0 CARNMT1  1 0.527 3
 UniProt:O15379 HDAC3  2 0.524 2
 UniProt:P43355 MAGA1      0.524 2
 UniProt:O43463 SUV39H1  1 0.524 3
 UniProt:Q9UIS9 MBD1  2 0.524 2
 UniProt:Q92841-4 DDX17      0.524 3
 UniProt:O00422 SAP18  1 0.524 2
 UniProt:P03129 VE7      0.524 2
 UniProt:Q66K89 E4F1      0.524 3
 UniProt:P29128 ICP0      0.524 2
 UniProt:P06748 NPM1  11 0.524 2
 UniProt:P51858 HDGF  1 0.512 4
 UniProt:Q92949 FOXJ1      0.508 2
 UniProt:Q13227 GPS2  1 0.499 2
 IntAct:EBI-2694074 MDM2      0.499 2
 UniProt:Q15466 NR0B2  1 0.499 2
 UniProt:P51610 HCFC1  2 0.499 2
 UniProt:Q9UER7 DAXX  13 0.499 2
 UniProt:Q99684 GFI1  1 0.499 4
 UniProt:Q9UKG1 APPL1  1 0.483 2
 UniProt:A4PIW0 A4PIW0      0.462 3
 UniProt:P46531 NOTCH1  20 0.462 2
 UniProt:P23771 GATA3  2 0.462 4
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