SUMOylation of CBX5 with SUMO1

Stable Identifier
R-HSA-4615933
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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As inferred from mouse homologs, CBX5 (HP1 alpha) is SUMOylated at lysine-84 and other lysine residues with SUMO1. SUMOylated CBX5 associates with long non-coding transcripts in pericentric heterochromatin and SUMOylation is required for initial targeting of CBX5 to pericentric domains.
Participants
Participates
Catalyst Activity

SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm]

Inferred From
Authored
Reviewed
Created
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