SUMOylation of RAD52 with SUMO1

Stable Identifier
R-HSA-4568863
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
SUMOylation of RAD52 with SUMO1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

RAD52 is SUMOylated at lysine-411, lysine-412, and lysine-414 with SUMO1. SUMOylation is important for localization of RAD52 to the nucleus.

Literature References
PubMed ID Title Journal Year
20190268 The putative nuclear localization signal of the human RAD52 protein is a potential sumoylation site

Kagawa, W, Kurumizaka, H, Suzuki, H, Saito, K, Suzuki, T, Dohmae, N, Tashiro, S, Saitoh, H, Yokoyama, S

J. Biochem. 2010
Participants
Input
Output
Participates
as an event of
Catalyst Activity

SUMO transferase activity of SUMO1:C93-UBE2I [cytoplasm]

Physical Entity
SUMO1:C93-UBE2I [nucleoplasm] (Homo sapiens)
Activity
SUMO transferase activity (GO:0019789)
Orthologous Events
SUMOylation of RAD52 with SUMO1 (Danio rerio)
SUMOylation of RAD52 with SUMO1 (Dictyostelium discoideum)
SUMOylation of RAD52 with SUMO1 (Gallus gallus)
SUMOylation of RAD52 with SUMO1 (Mus musculus)
SUMOylation of RAD52 with SUMO1 (Rattus norvegicus)
SUMOylation of RAD52 with SUMO1 (Saccharomyces cerevisiae)
SUMOylation of RAD52 with SUMO1 (Schizosaccharomyces pombe)
SUMOylation of RAD52 with SUMO1 (Xenopus tropicalis)
Authored
May, B  (2013-09-14)
Reviewed
Ferrari, S  (2015-02-21)
Created
May, B  (2013-09-19)
Cite Us!