PIAS1,2-1 SUMOylate XRCC4 at lysine-210 with SUMO1 (Yurchenko et al. 2006). SUMOylation causes localization of XRCC4 to the nucleus. (An unSUMOylatable mutant of XRCC4 is localized to the cytosol.)
Xue, Z, Sadofsky, MJ, Yurchenko, V
SUMO transferase activity of PIAS1,2-1 [nucleoplasm]
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