Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
AcK6-HIST1H2BH [nucleoplasm]
Stable Identifier
R-HSA-4568718
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HATs acetylate histones (Homo sapiens)
EP300 acetylates histone H2A, H2B, H3, H4 (Homo sapiens)
AcK-histone H2A, H2B, H3, H4 [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BH [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BH [nucleoplasm] (Homo sapiens)
HDACs deacetylate histones (Homo sapiens)
HDAC10 deacetylates histone (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BH [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BH [nucleoplasm] (Homo sapiens)
HDAC1:2-containing complex deacetylate histones (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BH [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BH [nucleoplasm] (Homo sapiens)
HDAC3 containing complexes deacetylate histone (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BH [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BH [nucleoplasm] (Homo sapiens)
HDAC8 deacetylates histones (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BH [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BH [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Early Events (Homo sapiens)
Activation of Latent HCMV Genome (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BH [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BH [nucleoplasm] (Homo sapiens)
Delayed Early (DE) Gene Expression (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BH [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BH [nucleoplasm] (Homo sapiens)
Immediate Early (IE) Gene Expression (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BH [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BH [nucleoplasm] (Homo sapiens)
Transcriptional Activation of the HCMV Genome (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BH [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BH [nucleoplasm] (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BH [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BH [nucleoplasm] (Homo sapiens)
HCMV Late Events (Homo sapiens)
Late (L) Gene Expression (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BH [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BH [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q93079 H2BC9
Gene Names
H2BC9, H2BFJ, HIST1H2BH
Chain
initiator methionine:, chain:2-126
Reference Genes
BioGPS Gene:8345 H2BC9
COSMIC (genes):HIST1H2BH H2BC9
CTD Gene:8345 H2BC9
dbSNP Gene:8345 H2BC9
ENSEMBL:ENSG00000275713 HIST1H2BH
HGNC:4755 H2BC9
KEGG:hsa:8345 H2BC9
Monarch:8345 H2BC9
NCBI Gene:8345 H2BC9
OMIM:602806 H2BC9
UCSC:Q93079 H2BC9
Reference Transcript
RefSeq:NM_003524.2 H2BC9
Other Identifiers
11715132_x_at
11759110_a_at
11759111_x_at
17005600
208546_3p_x_at
208546_PM_x_at
208546_x_at
2899200
2899252
2899253
8117426
8345
A_23_P366216
GO:0000786
GO:0003677
GO:0005198
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005829
GO:0006325
GO:0006334
GO:0019899
GO:0030527
GO:0032991
GO:0043226
GO:0043229
GO:0044389
GO:0046982
GO:0065003
GO:0070062
GO:0097677
HMNXSV003024103
ILMN_1688666
PH_hs_0029489
TC06000176.hg
g4504268_3p_x_at
Participates
as a member of
AcK(6,13,16,21)-HIST1H2BH [nucleoplasm] (Homo sapiens)
Other forms of this molecule
Ub-HIST1H2BH [nucleoplasm]
AcK-HIST1H2BH [nucleoplasm]
HIST1H2BH [extracellular region]
AcK16-HIST1H2BH [nucleoplasm]
AcK21-HIST1H2BH [nucleoplasm]
AcK13-HIST1H2BH [nucleoplasm]
Ub-121-HIST1H2BH [nucleoplasm]
HIST1H2BH [nucleoplasm]
Inferred To
H2Bv2 [nucleoplasm]
(Dictyostelium discoideum)
H2bc14 [nucleoplasm]
(Mus musculus)
htb1 [nucleoplasm]
(Schizosaccharomyces pombe)
HIST1H2BI [nucleoplasm]
(Bos taurus)
AcK6-HIST1H2BC [nucleoplasm]
(Danio rerio)
HIST1H2B5L [nucleoplasm]
(Gallus gallus)
H2B-V [nucleoplasm]
(Gallus gallus)
H2Bv3 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VII [nucleoplasm]
(Gallus gallus)
Homologues of AcK6-HIST1H2BC [nucleoplasm]
(Danio rerio)
Homologues of AcK6-HIST1H2BC [nucleoplasm]
(Gallus gallus)
Homologues of AcK6-HIST1H2BC [nucleoplasm]
(Xenopus tropicalis)
H2B-I [nucleoplasm]
(Gallus gallus)
HTB2 [nucleoplasm]
(Saccharomyces cerevisiae)
H2Bv1 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VIII [nucleoplasm]
(Gallus gallus)
His2B [nucleoplasm]
(Drosophila melanogaster)
AcK6-HIST1H2BB [nucleoplasm]
(Plasmodium falciparum)
h2bc11 [nucleoplasm]
(Xenopus tropicalis)
Homologues of AcK6-HIST1H2BB [nucleoplasm]
(Dictyostelium discoideum)
Homologues of AcK6-HIST1H2BB [nucleoplasm]
(Plasmodium falciparum)
Homologues of AcK6-HIST1H2BB [nucleoplasm]
(Saccharomyces cerevisiae)
si:ch211-113a14.22 [nucleoplasm]
(Danio rerio)
LOC100498553 [nucleoplasm]
(Xenopus tropicalis)
LOC116411635 [nucleoplasm]
(Xenopus tropicalis)
hist2h2l [nucleoplasm]
(Danio rerio)
HTB1 [nucleoplasm]
(Saccharomyces cerevisiae)
LOC570661 [nucleoplasm]
(Danio rerio)
h2bc21 [nucleoplasm]
(Xenopus tropicalis)
Modified Residues
Name
N6-acetyl-L-lysine at 6
Coordinate
6
PsiMod Name
N6-acetyl-L-lysine [MOD:00064]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.
Cross References
RefSeq
NP_003515.1
ENSEMBL
ENST00000619466
,
ENSP00000479169
OpenTargets
ENSG00000275713
HPA
ENSG00000275713-H2BC9
PRO
Q93079
Pharos - Targets
Q93079
GlyGen
Q93079
PDB
8OL1
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
18
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.527
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text