Reactome | AcK13-HIST1H2BJ [nucleoplasm]

AcK13-HIST1H2BJ

Stable Identifier

R-HSA-4568662

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

Chromatin organization (Homo sapiens)

- Chromatin modifying enzymes (Homo sapiens)
  - HATs acetylate histones (Homo sapiens)
    - CREBBP acetylates histone H2B, H3, H4 (Homo sapiens)
      - AcK-histone H2B, H3, H4 [nucleoplasm] (Homo sapiens)
        
        AcK13-replicative histone H2B [nucleoplasm] (Homo sapiens)
        
        Ack13-replicative histone HIST1H2B [nucleoplasm] (Homo sapiens)
        
        AcK13-HIST1H2BJ [nucleoplasm] (Homo sapiens)
    - EP300 acetylates histone H2A, H2B, H3, H4 (Homo sapiens)
      - AcK-histone H2A, H2B, H3, H4 [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-HIST1H2BJ [nucleoplasm] (Homo sapiens)
        
        AcK13-HIST1H2BJ [nucleoplasm] (Homo sapiens)
  - HDACs deacetylate histones (Homo sapiens)
    - HDAC1/2 containing-complexes deacetylate histones (Homo sapiens)
      - Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-HIST1H2BJ [nucleoplasm] (Homo sapiens)
        
        AcK13-HIST1H2BJ [nucleoplasm] (Homo sapiens)
    - HDAC10 deacetylates histone (Homo sapiens)
      - Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-HIST1H2BJ [nucleoplasm] (Homo sapiens)
        
        AcK13-HIST1H2BJ [nucleoplasm] (Homo sapiens)
    - HDAC3 containing complexes deacetylate histone (Homo sapiens)
      - Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-HIST1H2BJ [nucleoplasm] (Homo sapiens)
        
        AcK13-HIST1H2BJ [nucleoplasm] (Homo sapiens)
    - HDAC8 deacetylates histones (Homo sapiens)
      - Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
        
        AcK(6,13,16,21)-HIST1H2BJ [nucleoplasm] (Homo sapiens)
        
        AcK13-HIST1H2BJ [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:P06899 HIST1H2BJ

Gene Names

HIST1H2BJ, H2BFR

Chain

initiator methionine:1, chain:2-126

Reference Genes

BioGPS Gene:8970 HIST1H2BJ

COSMIC (genes):HIST1H2BJ HIST1H2BJ

CTD Gene:8970 HIST1H2BJ

dbSNP Gene:8970 HIST1H2BJ

ENSEMBL:ENSG00000124635 HIST1H2BJ

HGNC:4761 HIST1H2BJ

KEGG Gene (Homo sapiens):hsa:8970 HIST1H2BJ

Monarch:8970 HIST1H2BJ

NCBI Gene:8970 HIST1H2BJ

OMIM:615044 HIST1H2BJ

UCSC:P06899 HIST1H2BJ

Reference Transcript

RefSeq:NM_021058.3 HIST1H2BJ

Other Identifiers

0006400546

11741699_at

11741700_s_at

11741701_x_at

153_f_at

17016451

2946700

2946709

2946710

2946711

2946712

2RVQ

3A6N

3AFA

3AN2

3AV1

3AV2

3AYW

3AZE

3AZF

3AZG

3AZH

3AZI

3AZJ

3AZK

3AZL

3AZM

3AZN

3W96

3W97

3W98

3W99

3WA9

3WAA

3WTP

42205

43013

48671

4CAY

4YM5

4YM6

4Z5T

5AV5

5AV6

5AV8

5AV9

5AVB

5AVC

5AY8

5B0Y

5B0Z

5B24

5B2I

5B2J

5B31

5B32

5B33

5B40

5CPI

5CPJ

5CPK

5FUG

5GSE

5GTC

5GXQ

5JRG

5VEY

5X7X

5XF3

5XF4

5XF5

7970544

8124484

85177_at

8970

A0A024RCJ2

A_24_P55148

AAN06693

AF531293

AK311849

AL021807

BAG34791

CAA24950

CCDS4618

CH471081

EAX03080

EAX03081

ENSG00000124635

ENSP00000342886

ENSP00000476136

ENST00000339812

ENST00000607124

EntrezGene:8970

GE85150

GO:0000786

GO:0001530

GO:0002227

GO:0002376

GO:0003674

GO:0003677

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0005886

GO:0006334

GO:0006464

GO:0006950

GO:0007165

GO:0008150

GO:0008289

GO:0010804

GO:0016567

GO:0019731

GO:0022607

GO:0031640

GO:0042742

GO:0043226

GO:0046982

GO:0050829

GO:0050830

GO:0051276

GO:0061844

GO:0065003

HGNC:4761

HIST1H2BJ

HIST1H2BJ-201

HIST1H2BJ-203

HPA042205

HPA043013

HPA048671

ILMN_1658702

IPR000558

IPR007125

IPR009072

MIM:615044

NM_021058

NP_066402

PF00125

PH_hs_0035577

PR00621

SM00427

TC06001385.hg

TC06001386.hg

uc003niv.4

uc063miy.1

UPI0000001BD5

X00088

X00088_at

Participant Of

hasMember

Other forms of this molecule

HIST1H2BJ [extracellular region]

Ub-HIST1H2BJ [nucleoplasm]

AcK-HIST1H2BJ [nucleoplasm]

AcK21-HIST1H2BJ [nucleoplasm]

AcK6-HIST1H2BJ [nucleoplasm]

AcK16-HIST1H2BJ [nucleoplasm]

Ub-121-HIST1H2BJ [nucleoplasm]

HIST1H2BJ [nucleoplasm]

Inferred To

AcK13-HIST1H2BJ [nucleoplasm] (Canis familiaris)

AcK13-HIST1H2BJ [nucleoplasm] (Mus musculus)

AcK13-HIST1H2BJ [nucleoplasm] (Sus scrofa)

AcK13-HIST1H2BB [nucleoplasm] (Drosophila melanogaster)

AcK13-HIST1H2BB [nucleoplasm] (Saccharomyces cerevisiae)

AcK13-HIST1H2BB [nucleoplasm] (Schizosaccharomyces pombe)

AcK13-HIST1H2BB [nucleoplasm] (Xenopus tropicalis)

Homologues of AcK13-HIST1H2BB [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of AcK13-HIST1H2BB [nucleoplasm] (Xenopus tropicalis)

Modified Residues

Name

N6-acetyl-L-lysine at 13

Coordinate

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Cross References

RefSeq

NP_066402.2

GeneCards

P06899

DOCK Blaster

3WTP, 3A6N, 4CAY, 3W98, 5B24, 3AN2, 5FUG, 5B0Y, 5B0Z, 5CPI, 5AV8, 5JRG, 5B40, 3AFA, 5AVC, 5AVB, 3WAA, 3W96, 3AZE, 3W99, 5AV9, 3AZN, 5AV6, 5X7X, 3AZF, 3AZL, 5GSE, 5AY8, 5CPJ, 5B33, 5B31, 3WA9, 3AZM, 3AV2, 4YM5, 3AZK, 4YM6, 3AV1, 5CPK, 4Z5T, 5B32, 5AV5, 3W97, 3AZH, 3AZG, 5GXQ, 5B2J, 3AZJ, 3AYW, 3AZI, 5B2I

PRO

P06899

PDB

3AZJ, 5XF4, 5CPK, 3W96, 5B2J, 5B0Y, 5GTC, 2RVQ, 3W98, 6BUZ, 5AY8, 3AZK, 5XF5, 5B0Z, 3A6N, 3WA9, 5CPI, 5AV5, 3AZM, 5B40, 5JRG, 5AV6, 5B24, 3AV2, 5GXQ, 3AYW, 3AN2, 5GSE, 5AVB, 3AFA, 3AZH, 5VEY, 5AV8, 3AZE, 5AV9, 5B32, 4YM6, 5FUG, 3AZN, 5B31, 4Z5T, 5XF3, 3AZI, 5AVC, 4YM5, 5B2I, 4CAY, 3AV1, 5B33, 3W97, 3WTP, 5X7X, 3AZL, 3AZF, 3AZG, 5CPJ, 3W99, 3WAA