Reactome | Ack-HIST1H2AH [nucleoplasm]

Ack-HIST1H2AH [nucleoplasm]

Stable Identifier

R-HSA-4551333

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - HCMV Infection (Homo sapiens)
      - HCMV Early Events (Homo sapiens)
        
        Activation of Latent HCMV Genome (Homo sapiens)
        
        Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
        
        Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK-histone H2A [nucleoplasm] (Homo sapiens)
        
        AcK-histone HIST1H2A [nucleoplasm] (Homo sapiens)
        
        Ack-HIST1H2AH [nucleoplasm] (Homo sapiens)
        
        Delayed Early (DE) Gene Expression (Homo sapiens)
        
        Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
        
        Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK-histone H2A [nucleoplasm] (Homo sapiens)
        
        AcK-histone HIST1H2A [nucleoplasm] (Homo sapiens)
        
        Ack-HIST1H2AH [nucleoplasm] (Homo sapiens)
        
        Immediate Early (IE) Gene Expression (Homo sapiens)
        
        Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
        
        Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK-histone H2A [nucleoplasm] (Homo sapiens)
        
        AcK-histone HIST1H2A [nucleoplasm] (Homo sapiens)
        
        Ack-HIST1H2AH [nucleoplasm] (Homo sapiens)
        
        Transcriptional Activation of the HCMV Genome (Homo sapiens)
        
        Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK-histone H2A [nucleoplasm] (Homo sapiens)
        
        AcK-histone HIST1H2A [nucleoplasm] (Homo sapiens)
        
        Ack-HIST1H2AH [nucleoplasm] (Homo sapiens)
        
        Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
        
        Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK-histone H2A [nucleoplasm] (Homo sapiens)
        
        AcK-histone HIST1H2A [nucleoplasm] (Homo sapiens)
        
        Ack-HIST1H2AH [nucleoplasm] (Homo sapiens)
      - HCMV Late Events (Homo sapiens)
        
        Late (L) Gene Expression (Homo sapiens)
        
        Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
        
        Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
        
        Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
        
        AcK-histone H2A [nucleoplasm] (Homo sapiens)
        
        AcK-histone HIST1H2A [nucleoplasm] (Homo sapiens)
        
        Ack-HIST1H2AH [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96KK5 H2AC12

Gene Names

H2AC12, HIST1H2AH, HIST1H2AI

Chain

initiator methionine:1, chain:2-128

Reference Genes

BioGPS Gene:85235 H2AC12

CTD Gene:85235 H2AC12

dbSNP Gene:85235 H2AC12

ENSEMBL:ENSG00000274997 HIST1H2AH

ENSEMBL:ENSG00000274997.2 H2AC12

HGNC:13671 H2AC12

KEGG Gene (Homo sapiens):85235 H2AC12

Monarch:85235 H2AC12

NCBI Gene:85235 H2AC12

OMIM:615013 H2AC12

UCSC:Q96KK5 H2AC12

Reference Transcript

RefSeq:NM_080596.2 H2AC12

Other Identifiers

11736918_x_at

2899773

2899774

31992_f_at

8117543

85235

ADDON002756.hg

A_14_P104729

A_23_P81859

GO:0000786

GO:0003674

GO:0003677

GO:0005198

GO:0005576

GO:0005615

GO:0005634

GO:0005694

GO:0008150

GO:0030527

GO:0043226

GO:0043229

GO:0046982

GO:0070062

HMNXSV003016793

ILMN_2188451

PH_hs_0032806

TC06000225.hg

Participates

as a member of

AcK-histone HIST1H2A [nucleoplasm] (Homo sapiens)

Other forms of this molecule

K63polyUb-HIST1H2AH [nucleoplasm]

Ub-HIST1H2AH [nucleoplasm]

Ack6-HIST1H2AH [nucleoplasm]

Me2aR30-HIST1H2AH [nucleoplasm]

MeR30-HIST1H2AH [nucleoplasm]

Me2aR4-HIST1H2AH [nucleoplasm]

MeR4-HIST1H2AH [nucleoplasm]

Me2sR4-HIST1H2AH [nucleoplasm]

Me2aR12-HIST1H2AH [nucleoplasm]

MeR12-HIST1H2AH [nucleoplasm]

HIST1H2AH [nucleoplasm]

Inferred To

Homologues of Ack-HIST1H2AH [nucleoplasm] (Danio rerio)

Homologues of Ack-HIST1H2AH [nucleoplasm] (Xenopus tropicalis)

LOC100485548 [nucleoplasm] (Xenopus tropicalis)

h2ax [nucleoplasm] (Danio rerio)

h2ax [nucleoplasm] (Xenopus tropicalis)

LOC100148591 [nucleoplasm] (Danio rerio)

h2ac14 [nucleoplasm] (Xenopus tropicalis)

LOC100487632 [nucleoplasm] (Xenopus tropicalis)

LOC116407737 [nucleoplasm] (Xenopus tropicalis)

h2ac12 [nucleoplasm] (Xenopus tropicalis)

Ack-HIST1H2AH [nucleoplasm] (Bos taurus)

Ack-HIST1H2AH [nucleoplasm] (Canis familiaris)

Ack-HIST1H2AH [nucleoplasm] (Xenopus tropicalis)

h2ax.2 [nucleoplasm] (Xenopus tropicalis)

LOC100491383 [nucleoplasm] (Xenopus tropicalis)

LOC101734900 [nucleoplasm] (Xenopus tropicalis)

Modified Residues

Name

N6-acetyl-L-lysine at unknown position

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Cross References

RefSeq

NP_542163.1

OpenTargets

ENSG00000274997

HPA

ENSG00000274997-H2AC12

GeneCards

Q96KK5

Ensembl

ENSG00000274997, ENST00000377459, ENSP00000366679

PRO

Q96KK5

Pharos - Targets

Q96KK5

HMDB Protein

HMDBP07728