PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP

Stable Identifier
R-HSA-453338
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP
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Cytosolic, non-phosphorylated PGYM dimers (b form) complexed with AMP can reversibly dissociate (Rath et al. 2000).
Literature References
PubMed ID Title Journal Year
10949035 Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core

Danley, DE, Mansour, MN, Ammirati, M, Pandit, J, Schulte, GK, LeMotte, PK, Wasilko, DJ, Fennell, KF, Rath, VL, Hynes, TR

Mol Cell 2000
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Event Information
Reverse Reaction
PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex (Homo sapiens)
Orthologous Events
PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Bos taurus)
PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Caenorhabditis elegans)
PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Canis familiaris)
PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Danio rerio)
PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Dictyostelium discoideum)
PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Drosophila melanogaster)
PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Mus musculus)
PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Rattus norvegicus)
PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Saccharomyces cerevisiae)
PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Sus scrofa)
PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Xenopus tropicalis)
PYGB b dimer:AMP complex <=> PGYB dimer, b form + 2 AMP (Homo sapiens)
Authored
D'Eustachio, P  (2010-01-22)
Created
D'Eustachio, P  (2010-01-22)
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