Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
GSC [nucleoplasm]
Stable Identifier
R-HSA-452569
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Homeobox protein goosecoid, GSC_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Gastrulation (Homo sapiens)
Formation of definitive endoderm (Homo sapiens)
Expression of GSC in definitive endoderm (Homo sapiens)
GSC [nucleoplasm] (Homo sapiens)
Germ layer formation at gastrulation (Homo sapiens)
Expression of Goosecoid (GSC) in the primitive streak (Homo sapiens)
GSC [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P56915 GSC
Gene Names
GSC
Chain
chain:1-257
Reference Genes
BioGPS Gene:145258 GSC
COSMIC (genes):GSC GSC
CTD Gene:145258 GSC
dbSNP Gene:145258 GSC
ENSEMBL:ENSG00000133937 GSC
HGNC:4612 GSC
KEGG:hsa:145258 GSC
Monarch:145258 GSC
NCBI Gene:145258 GSC
OMIM:138890 GSC
UCSC:P56915 GSC
Reference Transcript
RefSeq:NM_173849.2 GSC
Other Identifiers
11730165_at
145258
1552338_PM_at
1552338_at
16796313
3577786
3577787
3577788
3577790
3577791
3577792
3577793
3577794
3577795
3577796
7981106
A_23_P76774
A_24_P232809
GE538801
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001227
GO:0003677
GO:0005634
GO:0005667
GO:0006355
GO:0006357
GO:0007369
GO:0009653
GO:0014036
GO:0016055
GO:0021904
GO:0023019
GO:0030178
GO:0030900
GO:0042474
GO:0043226
GO:0043583
GO:0048644
GO:0048704
GO:0048856
GO:0061629
GO:0140110
GO:1990837
HMNXSV003047412
Hs2.437095.1.A1_3p_at
ILMN_1655849
PH_hs_0020947
TC14001470.hg
Participates
as an output of
Expression of Goosecoid (GSC) in the primitive streak (Homo sapiens)
Expression of GSC in definitive endoderm (Homo sapiens)
Cross References
ENSEMBL
ENSG00000133937
,
ENST00000238558
,
ENSP00000238558
OpenTargets
ENSG00000133937
GeneCards
GSC
HPA
ENSG00000133937-GSC
PRO
P56915
Pharos - Targets
P56915
PDB
2DMU
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text