Edited GRIK 1 (GluR5) [plasma membrane]

Stable Identifier
R-HSA-451322
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
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General

Glutamine at position 636 is replaced by arginine in an editing step which occurs posttranscriptionally.

External Reference Information
External Reference
UniProt:P39086 GRIK1
Gene Names
GRIK1, GLUR5
Chain
signal peptide:1-30, chain:31-918
Reference Genes
BioGPS Gene:2897 GRIK1
COSMIC (genes):GRIK1 GRIK1
CTD Gene:2897 GRIK1
dbSNP Gene:2897 GRIK1
ENSEMBL:ENSG00000171189 GRIK1
HGNC:4579 GRIK1
KEGG Gene (Homo sapiens):2897 GRIK1
Monarch:2897 GRIK1
NCBI Gene:2897 GRIK1
OMIM:138245 GRIK1
UCSC:P39086 GRIK1
Reference Transcript
Other Identifiers
0003830053
0004480048
0006110309
11732802_a_at
11734484_a_at
16924761
207242_s_at
214611_at
2897
35855_s_at
35856_r_at
35857_at
3928227
3928228
3928229
3928242
3928243
3928244
3928246
3928253
3928259
3928263
3928265
3928266
3928267
3928269
3928271
3928280
3928285
3928286
3928294
3928296
3928297
3928299
3928326
3928327
8069770
A_23_P109286
GE80957
GO:0003674
GO:0004970
GO:0005216
GO:0005575
GO:0005886
GO:0005887
GO:0006810
GO:0006811
GO:0007165
GO:0007215
GO:0007267
GO:0007268
GO:0007399
GO:0007417
GO:0008066
GO:0008150
GO:0015276
GO:0015277
GO:0016020
GO:0016021
GO:0022857
GO:0030054
GO:0034220
GO:0035235
GO:0035249
GO:0038023
GO:0045202
GO:0045211
GO:0048856
GO:0050804
GO:0051966
GO:0055085
GO:0060078
GO:1904315
HMNXSV003028433
Hs.181581.1.S2_3p_at
ILMN_1651817
ILMN_1682583
ILMN_1773114
L19058_at
PH_hs_0023125
TC21000360.hg
g4504116_3p_a_at
g4504116_3p_x_at
Participates
as a component of
Other forms of this molecule
GRIK1 [plasma membrane]
Inferred To
Grik1 [plasma membrane] (Mus musculus)
Grik1 [plasma membrane] (Rattus norvegicus)
GRIK1 [plasma membrane] (Canis familiaris)
GRIK1 [plasma membrane] (Gallus gallus)
GRIK1 [plasma membrane] (Sus scrofa)
Ekar [plasma membrane] (Drosophila melanogaster)
grik1b [plasma membrane] (Danio rerio)
Homologues of Edited GRIK 1 (GluR5) [plasma membrane] (Drosophila melanogaster)
DmelCG11155 [plasma membrane] (Drosophila melanogaster)
Modified Residues
Name
L-glutamine 636 replaced with L-arginine
Coordinate
636
PsiMod
L-arginine residue [MOD:00011]
A protein modification that effectively converts a source amino acid residue to an L-arginine.
L-glutamine removal [MOD:01637]
A protein modification that effectively removes or replaces an L-glutamine.
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
450
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
GlyGen
PDB
ZINC - Investigational
ZINC - Metabolites
GeneCards
HPA
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
HMDB Protein
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