Edited GRIK 1 (GluR5) [plasma membrane]

Stable Identifier
R-HSA-451322
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
General

Glutamine at position 636 is replaced by arginine in an editing step which occurs posttranscriptionally.

External Reference Information
External Reference
UniProt:P39086 GRIK1
Gene Names
GRIK1, GLUR5
Chain
signal peptide:1-30, chain:31-918
Reference Genes
BioGPS Gene:2897 GRIK1
COSMIC (genes):GRIK1 GRIK1
CTD Gene:2897 GRIK1
dbSNP Gene:2897 GRIK1
ENSEMBL:ENSG00000171189 GRIK1
HGNC:4579 GRIK1
KEGG Gene (Homo sapiens):2897 GRIK1
Monarch:2897 GRIK1
NCBI Gene:2897 GRIK1
OMIM:138245 GRIK1
UCSC:P39086 GRIK1
Reference Transcript
Other Identifiers
0003830053
0004480048
0006110309
11732802_a_at
11734484_a_at
16924761
207242_PM_s_at
207242_s_at
214611_PM_at
214611_at
2897
35855_s_at
35856_r_at
35857_at
3928227
3928228
3928229
3928242
3928243
3928244
3928246
3928253
3928259
3928263
3928265
3928266
3928267
3928269
3928271
3928280
3928285
3928286
3928294
3928296
3928297
3928299
3928326
3928327
8069770
A_23_P109286
GE80957
GO:0003674
GO:0004970
GO:0005216
GO:0005575
GO:0005622
GO:0005886
GO:0005887
GO:0006810
GO:0006811
GO:0007165
GO:0007215
GO:0007267
GO:0007268
GO:0007399
GO:0007417
GO:0008066
GO:0008150
GO:0015276
GO:0015277
GO:0016020
GO:0016021
GO:0022857
GO:0030054
GO:0034220
GO:0035235
GO:0035249
GO:0038023
GO:0043226
GO:0043231
GO:0045202
GO:0045211
GO:0048856
GO:0050804
GO:0051966
GO:0055085
GO:0060078
GO:1904315
HMNXSV003028433
Hs.181581.1.S2_3p_at
ILMN_1651817
ILMN_1682583
ILMN_1773114
L19058_at
PH_hs_0023125
TC21000360.hg
g4504116_3p_a_at
g4504116_3p_x_at
Participates
as a component of
Other forms of this molecule
GRIK1 [plasma membrane]
Inferred To
GRIK1 [plasma membrane] (Bos taurus)
GRIK1 [plasma membrane] (Canis familiaris)
GRIK1 [plasma membrane] (Gallus gallus)
GRIK1 [plasma membrane] (Sus scrofa)
glr-4 [plasma membrane] (Caenorhabditis elegans)
GluRIIA [plasma membrane] (Drosophila melanogaster)
Ekar [plasma membrane] (Drosophila melanogaster)
grik1b [plasma membrane] (Danio rerio)
grik1 [plasma membrane] (Xenopus tropicalis)
GluRIIE [plasma membrane] (Drosophila melanogaster)
GluRIIB [plasma membrane] (Drosophila melanogaster)
Ir21a [plasma membrane] (Drosophila melanogaster)
Ir75d [plasma membrane] (Drosophila melanogaster)
GluRIID [plasma membrane] (Drosophila melanogaster)
DmelCG11155 [plasma membrane] (Drosophila melanogaster)
Grik [plasma membrane] (Drosophila melanogaster)
Grik1 [plasma membrane] (Mus musculus)
Grik1 [plasma membrane] (Rattus norvegicus)
GluRIIC [plasma membrane] (Drosophila melanogaster)
glr-6 [plasma membrane] (Caenorhabditis elegans)
glr-3 [plasma membrane] (Caenorhabditis elegans)
glr-5 [plasma membrane] (Caenorhabditis elegans)
KaiR1D [plasma membrane] (Drosophila melanogaster)
Homologues of Edited GRIK 1 (GluR5) [plasma membrane] (Caenorhabditis elegans)
Homologues of Edited GRIK 1 (GluR5) [plasma membrane] (Drosophila melanogaster)
clumsy [plasma membrane] (Drosophila melanogaster)
Modified Residues
Name
L-glutamine 636 replaced with L-arginine
Coordinate
636
PsiMod
L-glutamine removal [MOD:01637]
A protein modification that effectively removes or replaces an L-glutamine.
L-arginine residue [MOD:00011]
A protein modification that effectively converts a source amino acid residue to an L-arginine.
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
450
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
ZINC - Investigational
ZINC - Metabolites
GeneCards
HPA
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
HMDB Protein
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