Activation of Edited Kainate receptors

Stable Identifier
R-HSA-451310
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane, cytosol
Locations in the PathwayBrowser
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Activation of Edited Kainate receptors
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The activation of Kainate receptors by glutamate in the postsynaptic neuron leads to influx of Na+ ions resulting in depolarization of the postsynaptic membrane.

Literature References
PubMed ID Title Journal Year
16221857 Q/R site editing controls kainate receptor inhibition by membrane fatty acids

Wilding, TJ, Zhou, Y, Huettner, JE

J Neurosci 2005
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
ligand-gated ion channel activity of Edited Kainate Receptor-glutamate complex [plasma membrane]
Physical Entity
Edited Kainate Receptor-glutamate complex [plasma membrane]
Activity
ligand-gated ion channel activity (0015276)
Orthologous Events
Activation of Edited Kainate receptors (Caenorhabditis elegans)
Activation of Edited Kainate receptors (Canis familiaris)
Activation of Edited Kainate receptors (Danio rerio)
Activation of Edited Kainate receptors (Drosophila melanogaster)
Activation of Edited Kainate receptors (Gallus gallus)
Activation of Edited Kainate receptors (Mus musculus)
Activation of Edited Kainate receptors (Rattus norvegicus)
Activation of Edited Kainate receptors (Sus scrofa)
Activation of Edited Kainate receptors (Xenopus tropicalis)
Cross References
Rhea
Authored
Mahajan, SS  (2010-01-15)
Reviewed
Tukey, D  (2009-11-18)
Created
Mahajan, SS  (2010-01-05)
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