Edited Kainate receptors

Stable Identifier
R-HSA-451279
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Kainate receptors are formed by the assembly of four subunits. GluR5-7 (GRIK, glutamate receptor, ionotropic Kainate 1-3) form functional homomers whereas, KA1 and KA2 or GRIK4,5 form functional heteromers with GRIK1/2/3. Kainate receptor subunits bind Cl- ion in the anion binding site in the ligand binding domain. The dimer is stabilized by the presence of one Cl- ion which binds within the dimer interface.

Participants
Participant Of
Inferred To