Mitochondrial fumarate hydratase catalyzes the reversible reaction of malate to form fumarate and water (Bourgeron et al. 1994). Unpublished crystallographic data indicate that the protein is a tetramer (PDB 3E04).
Chretien, D, Landrieu, P, Doonan, S, Bourgeron, T, Rabier, D, Poggi-Bach, J, Rötig, A, Letouzé, P, Munnich, A, Rustin, P
fumarate hydratase activity of FH tetramer [mitochondrial matrix]
© 2023 Reactome