Kainate Receptors [plasma membrane]

Stable Identifier
R-HSA-450885
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
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General
Kainate receptors are formed by the assembly of four subunits. GluR5-7 (GRIK, glutamate receptor, ionotropic Kainate 1-3) form functional homomers whereas, KA1 and KA2 or GRIK4,5 form functional heteromers with GRIK1/2/3. Kainate receptor subunits bind Cl- ion in the anion binding site in the ligand binding domain. The dimer is stabilized by the presence of one Cl- ion which binds within the dimer interface.
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Inferred To
GRIK 2 homomer [plasma membrane] (Caenorhabditis elegans)
Kainate Receptors [plasma membrane] (Bos taurus)
Kainate Receptors [plasma membrane] (Canis familiaris)
Kainate Receptors [plasma membrane] (Drosophila melanogaster)
Kainate Receptors [plasma membrane] (Gallus gallus)
Kainate Receptors [plasma membrane] (Mus musculus)
Kainate Receptors [plasma membrane] (Rattus norvegicus)
Kainate Receptors [plasma membrane] (Sus scrofa)
Kainate Receptors [plasma membrane] (Xenopus tropicalis)
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