KSRP binds AU-rich element in 3' UTR of mRNA

Stable Identifier
Reaction [binding]
Homo sapiens
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KSRP (KHSRP) binds AU-rich regions of target RNAs via its four K-homology (KH) domains (Syswam et al. 2005, Ruggiero et al. 2007, Garcia-Mayoral et al. 2008, Li et al. 2009, Schmidt et al. 2010).
Literature References
PubMed ID Title Journal Year
19141871 Identification of mRNA binding proteins that regulate the stability of LDL receptor mRNA through AU-rich elements

Zhou, Y, Chen, W, Liu, J, Abidi, P, Sharpe, O, Li, H, Kraemer, FB, Robinson, WH

J Lipid Res 2009
17437629 Identification of a set of KSRP target transcripts upregulated by PI3K-AKT signaling

Khabar, KS, Ruggiero, T, Chen, CY, Trabucchi, M, Gherzi, R, Ponassi, M, Briata, P, al-Haj, L, Corte, G

BMC Mol Biol 2007
15514971 IL-1beta induces stabilization of IL-8 mRNA in malignant breast cancer cells via the 3' untranslated region: Involvement of divergent RNA-binding factors HuR, KSRP and TIAR

Yang, X, Suswam, EA, Huang, Y, Nabors, LB, King, PH

Int J Cancer 2005
19854161 Transcriptional and post-transcriptional regulation of iNOS expression in human chondrocytes

Kleinert, H, Rauschkolb, P, Art, J, Pautz, A, Jung, M, Goldring, MB, Erkel, G, Schmidt, N

Biochem Pharmacol 2010
18684992 The sequence selectivity of KSRP explains its flexibility in the recognition of the RNA targets

Ramos, A, Garcia-Mayoral, MF, Diaz-Moreno, I, Hollingworth, D

Nucleic Acids Res 2008
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