Reactome | Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA

Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA

Stable Identifier

R-HSA-450517

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA

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Butyrate response factor 1 (BRF1) binds AU-rich elements in the 3' untranslated region of mRNAs.

Literature References

PubMed ID	Title	Journal	Year
17030608	BRF1 protein turnover and mRNA decay activity are regulated by protein kinase B at the same phosphorylation sites Benjamin, D, Schmidlin, M, Min, L, Gross, B, Moroni, C	Mol Cell Biol	2006
15538381	The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B Schmidlin, M, Lu, M, Leuenberger, SA, Stoecklin, G, Mallaun, M, Gross, B, Gherzi, R, Hess, D, Hemmings, BA, Moroni, C	EMBO J	2004
18326031	The AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2 Maitra, S, Chou, CF, Luber, CA, Lee, KY, Mann, M, Chen, CY	RNA	2008
12198173	Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover Stoecklin, G, Colombi, M, Raineri, I, Leuenberger, S, Mallaun, M, Schmidlin, M, Gross, B, Lu, M, Kitamura, T, Moroni, C	EMBO J	2002