Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA

Stable Identifier
R-HSA-450517
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Butyrate response factor 1 (BRF1) binds AU-rich elements in the 3' untranslated region of mRNAs.

Literature References
PubMed ID Title Journal Year
15538381 The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B

Schmidlin, M, Lu, M, Leuenberger, SA, Stoecklin, G, Mallaun, M, Gross, B, Gherzi, R, Hess, D, Hemmings, BA, Moroni, C

EMBO J 2004
17030608 BRF1 protein turnover and mRNA decay activity are regulated by protein kinase B at the same phosphorylation sites

Benjamin, D, Schmidlin, M, Min, L, Gross, B, Moroni, C

Mol Cell Biol 2006
18326031 The AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2

Maitra, S, Chou, CF, Luber, CA, Lee, KY, Mann, M, Chen, CY

RNA 2008
12198173 Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover

Stoecklin, G, Colombi, M, Raineri, I, Leuenberger, S, Mallaun, M, Schmidlin, M, Gross, B, Lu, M, Kitamura, T, Moroni, C

EMBO J 2002
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